MALT1

MALT1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2G7R, 3BFO, 3K0W, 3UO8, 3UOA, 3V4O, 3V55, 4I1P, 4I1R
Dynodwyr
Cyfenwau	MALT1, IMD12, MLT, MLT1, PCASP1, MALT1 paracaspase
Dynodwyr allanol	OMIM: 604860 HomoloGene: 4938 GeneCards: MALT1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • signal transducer activity • GO:0050372 ubiquitin-protein transferase activity • protease binding • protein self-association • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • kinase activator activity • cysteine-type endopeptidase activity • hydrolase activity • identical protein binding Cydrannau o'r gell • cytoplasm • Cellbilen • nucleolus • perinuclear region of cytoplasm • cnewyllyn cell • fibrillar center • cytosol • CBM complex Prosesau biolegol • regulation of apoptotic process • defense response • regulation of T cell receptor signaling pathway • negative regulation of apoptotic process • stimulatory C-type lectin receptor signaling pathway • activation of NF-kappaB-inducing kinase activity • proteolysis • Fc-epsilon receptor signaling pathway • T cell proliferation • B cell activation • response to fungus • positive regulation of T cell activation • positive regulation of interleukin-2 production • protein complex oligomerization • positive regulation of T cell cytokine production • positive regulation of I-kappaB kinase/NF-kappaB signaling • nuclear export • B-1 B cell differentiation • response to molecule of bacterial origin • positive regulation of protein ubiquitination • T cell receptor signaling pathway • protein ubiquitination • innate immune response • positive regulation of NF-kappaB transcription factor activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10892	n/a
Ensembl	ENSG00000172175	n/a
UniProt	Q9UDY8	n/a
RefSeq (mRNA)	NM_006785 NM_173844	n/a
RefSeq (protein)	NP_006776 NP_776216	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MALT1 yw MALT1 a elwir hefyd yn MALT1 paracaspase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18q21.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MALT1.

• MLT
• MLT1
• IMD12
• PCASP1

Llyfryddiaeth

• "MALT1 Protease Activity Controls the Expression of Inflammatory Genes in Keratinocytes upon Zymosan Stimulation. ". J Invest Dermatol. 2016. PMID 26767426.
• "The paracaspase MALT1 dampens NF-κB signalling by cleaving the LUBAC subunit HOIL-1. ". FEBS J. 2016. PMID 26716947.
• "A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma. ". Leukemia. 2017. PMID 27538487.
• "Deficiency in Mucosa-associated Lymphoid Tissue Lymphoma Translocation 1: A Novel Cause of IPEX-Like Syndrome. ". J Pediatr Gastroenterol Nutr. 2017. PMID 27253662.
• "Backbone Assignment of the MALT1 Paracaspase by Solution NMR.". PLoS One. 2016. PMID 26788853.