MAGI1

MAGI1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WBP, 2KPK, 2KPL, 2Q9V, 2R4H, 2YSD, 2YSE, 2ZAJ, 3BPU
Dynodwyr
Cyfenwau	MAGI1, AIP-3, AIP3, BAIAP1, BAP-1, BAP1, MAGI-1, Magi1d, TNRC19, WWP3, membrane associated guanylate kinase, WW and PDZ domain containing 1, MAGI-1b
Dynodwyr allanol	OMIM: 602625 HomoloGene: 31257 GeneCards: MAGI1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0032947 molecular adaptor activity • nucleotide binding • protein C-terminus binding • GO:0001948, GO:0016582 protein binding • ATP binding • alpha-actinin binding Cydrannau o'r gell • adherens junction • cell junction • Cellbilen • cell projection • bilen • cell-cell junction • nucleoplasm • bicellular tight junction • cnewyllyn cell • cytoplasm Prosesau biolegol • neuron death • cell surface receptor signaling pathway • cell adhesion • GO:0034622 protein-containing complex assembly • GO:0072468 signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9223	n/a
Ensembl	ENSG00000282956 ENSG00000151276	n/a
UniProt	Q96QZ7	n/a
RefSeq (mRNA)	NM_001033057 NM_004742 NM_015520 NM_001365903 NM_001365904 NM_001365905	n/a
RefSeq (protein)	NP_001028229 NP_004733 NP_056335 NP_001352832 NP_001352833 NP_001352834	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MAGI1 yw MAGI1 a elwir hefyd yn Membrane associated guanylate kinase, WW and PDZ domain containing 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3p14.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MAGI1.

• AIP3
• BAP1
• WWP3
• AIP-3
• BAP-1
• BAIAP1
• MAGI-1
• Magi1d
• TNRC19

Llyfryddiaeth

• "Structural basis for controlling the dimerization and stability of the WW domains of an atypical subfamily. ". Protein Sci. 2008. PMID 18562638.
• "MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion. ". Mol Biol Cell. 2006. PMID 16339077.
• "Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. ". JAMA Psychiatry. 2015. PMID 25993607.
• "Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM. ". PLoS One. 2012. PMID 22911767.
• "Downregulation of MAGI1 associates with poor prognosis of hepatocellular carcinoma.". J Invest Surg. 2012. PMID 21942217.