MAGEA4

MAGEA4
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1I4F, 2WA0
Dynodwyr
Cyfenwau	MAGEA4, CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MAGE family member A4
Dynodwyr allanol	OMIM: 300175 HomoloGene: 134073 GeneCards: MAGEA4
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • molecular function;
Cydrannau o'r gell	• cydran cellog;
Prosesau biolegol	• GO:0022610 proses fiolegol;
	Sources:Amigo / QuickGO
Orthologau
	4103
	n/a
	ENSG00000147381
	n/a
	P43358
	n/a
	NM_001011548; NM_001011549; NM_001011550; NM_002362
	n/a
	NP_001011548; NP_001011549; NP_001011550; NP_002353
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MAGEA4 yw MAGEA4 a elwir hefyd yn MAGE family member A4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq28.^[2]

Cyfystyron[golygu | golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MAGEA4.

CT1.4
MAGE4
MAGE4A
MAGE4B
MAGE-41
MAGE-X2

Llyfryddiaeth[golygu | golygu cod]

"Prospective evaluation of 64 serum autoantibodies as biomarkers for early detection of colorectal cancer in a true screening setting. ". Oncotarget. 2016. PMID 26909861.
"Potential role of 5-aza-2'-deoxycytidine induced MAGE-A4 expression in immunotherapy for anaplastic thyroid cancer. ". Surgery. 2013. PMID 24238058.
"Proteomic profiling of triple-negative breast carcinomas in combination with a three-tier orthogonal technology approach identifies Mage-A4 as potential therapeutic target in estrogen receptor negative breast cancer. ". Mol Cell Proteomics. 2013. PMID 23172894.
"Clinical significance of human leukocyte antigen loss and melanoma-associated antigen 4 expression in smokers of non-small cell lung cancer patients. ". Int J Clin Oncol. 2013. PMID 23124547.
"MAGEA4 induces growth in normal oral keratinocytes by inhibiting growth arrest and apoptosis.". Oncol Rep. 2012. PMID 22842486.

Cyfeiriadau[golygu | golygu cod]

[1] "Human PubMed Reference:".

[2] MAGEA4 - Cronfa NCBI

[1]

[2]