MAD1L1

MAD1L1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4DZO, 1GO4
Dynodwyr
Cyfenwau	MAD1L1, PIG9, TP53I9, TXBP181, MAD1, MAD1 mitotic arrest deficient like 1, mitotic arrest deficient 1 like 1
Dynodwyr allanol	OMIM: 602686 HomoloGene: 74500 GeneCards: MAD1L1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • kinetochore binding • identical protein binding Cydrannau o'r gell • centrosome • spindle pole • spindle • nuclear pore • Cromosom • microtubule organizing center • mitotic spindle • chromosome, centromeric region • Cytosgerbwd • kinetochore • cytoplasm • mitotic spindle pole • nuclear envelope • cnewyllyn cell • cytosol • nuclear pore nuclear basket Prosesau biolegol • regulation of mitotic cell cycle phase transition • regulation of metaphase plate congression • mitotic cell cycle checkpoint signaling • thymus development • Cellraniad • negative regulation of T cell proliferation • cell cycle • mitotic spindle assembly checkpoint signaling • attachment of mitotic spindle microtubules to kinetochore Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8379	n/a
Ensembl	ENSG00000002822	n/a
UniProt	Q9Y6D9	n/a
RefSeq (mRNA)	NM_001013836 NM_001013837 NM_001304523 NM_001304524 NM_001304525 NM_003550	n/a
RefSeq (protein)	NP_001013858 NP_001013859 NP_001291452 NP_001291453 NP_001291454 NP_003541	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MAD1L1 yw MAD1L1 a elwir hefyd yn Mitotic spindle assembly checkpoint protein MAD1 a Mitotic arrest deficient 1 like 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p22.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MAD1L1.

• MAD1
• PIG9
• TP53I9
• TXBP181

Llyfryddiaeth

• "Investigating the Impact of a Genome-Wide Supported Bipolar Risk Variant of MAD1L1 on the Human Reward System. ". Neuropsychopharmacology. 2016. PMID 27184339.
• "The spindle assembly checkpoint promotes chromosome bi-orientation: A novel Mad1 role in chromosome alignment. ". Cell Cycle. 2016. PMID 26752263.
• "Genetic association of GWAS-supported MAD1L1 gene polymorphism rs12666575 with schizophrenia susceptibility in a Chinese population. ". Neurosci Lett. 2016. PMID 26528791.
• "Mitotic arrest deficient-like 1 is correlated with poor prognosis in small-cell lung cancer after surgical resection. ". Tumour Biol. 2016. PMID 26499943.
• "A Golgi-localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration.". Curr Biol. 2014. PMID 25447996.