LYPLA1

LYPLA1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1FJ2
Dynodwyr
Cyfenwau	LYPLA1, APT-1, APT1, LPL-I, LPL1, hAPT1, lysophospholipase I, lysophospholipase 1
Dynodwyr allanol	OMIM: 605599 HomoloGene: 100781 GeneCards: LYPLA1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • lysophospholipase activity • hydrolase activity • lipase activity • palmitoyl-(protein) hydrolase activity • GO:0004091 carboxylic ester hydrolase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • cytosol • extracellular exosome • mitocondria Prosesau biolegol • protein depalmitoylation • regulation of nitric-oxide synthase activity • negative regulation of Golgi to plasma membrane protein transport • fatty acid metabolic process • lipid metabolism • metabolaeth Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10434	n/a
Ensembl	ENSG00000120992	n/a
UniProt	O75608 Q6IAQ1	n/a
RefSeq (mRNA)	NM_001279356 NM_001279357 NM_001279358 NM_001279359 NM_001279360 NM_006330	n/a
RefSeq (protein)	NP_001266285 NP_001266286 NP_001266287 NP_001266288 NP_001266289 NP_006321 NP_006321.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LYPLA1 yw LYPLA1 a elwir hefyd yn Acyl-protein thioesterase 1 a LYPLA1 protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q11.23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LYPLA1.

• APT1
• LPL1
• APT-1
• LPL-I
• hAPT1

Llyfryddiaeth

• "Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A. ". Structure. 2000. PMID 11080636.
• "Subcellular localization and PKC-dependent regulation of the human lysophospholipase A/acyl-protein thioesterase in WISH cells. ". Biochim Biophys Acta. 2000. PMID 10760470.
• "Identification and characterization of acyl-protein thioesterase 1/lysophospholipase I as a ghrelin deacylation/lysophospholipid hydrolyzing enzyme in fetal bovine serum and conditioned medium. ". Endocrinology. 2010. PMID 20685872.
• "A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. ". Nat Cell Biol. 2009. PMID 19465924.
• "Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1.". Biochim Biophys Acta. 2009. PMID 19439193.