LY96

LY96
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2E56, 2E59, 2Z65, 3FXI, 3ULA, 4G8A
Dynodwyr
Cyfenwau	LY96, ESOP-1, MD-2, MD2, ly-96, lymphocyte antigen 96
Dynodwyr allanol	OMIM: 605243 HomoloGene: 9109 GeneCards: LY96
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • coreceptor activity • GO:0001948, GO:0016582 protein binding • lipopolysaccharide immune receptor activity • lipopolysaccharide binding • Toll-like receptor 4 binding Cydrannau o'r gell • intrinsic component of plasma membrane • Cellbilen • extracellular region • lipopolysaccharide receptor complex • endosome membrane • extracellular space Prosesau biolegol • toll-like receptor 4 signaling pathway • immune system process • MyD88-dependent toll-like receptor signaling pathway • positive regulation of lipopolysaccharide-mediated signaling pathway • TRIF-dependent toll-like receptor signaling pathway • cellular defense response • cell surface receptor signaling pathway • response to lipopolysaccharide • positive regulation of tumor necrosis factor production • inflammatory response • cellular response to lipopolysaccharide • detection of lipopolysaccharide • I-kappaB kinase/NF-kappaB signaling • MyD88-independent toll-like receptor signaling pathway • lipopolysaccharide-mediated signaling pathway • negative regulation of MyD88-independent toll-like receptor signaling pathway • innate immune response • GO:0060554, GO:0060555 necroptosis • apoptotic signaling pathway • toll-like receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23643	n/a
Ensembl	ENSG00000154589	n/a
UniProt	Q9Y6Y9	n/a
RefSeq (mRNA)	NM_001195797 NM_015364	n/a
RefSeq (protein)	NP_001182726 NP_056179	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LY96 yw LY96 a elwir hefyd yn Lymphocyte antigen 96 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8q21.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LY96.

• MD2
• MD-2
• ly-96
• ESOP-1

Llyfryddiaeth

• "MD-2 regulates LPS-induced NLRP3 inflammasome activation and IL-1beta secretion by a MyD88/NF-κB-dependent pathway in alveolar macrophages cell line. ". Mol Immunol. 2017. PMID 28654770.
• "Identification of a novel transcript of human MD2 gene. ". Gene. 2016. PMID 27317890.
• "Genome-wide association study of new-onset atrial fibrillation after coronary artery bypass grafting surgery. ". Am Heart J. 2015. PMID 26385043.
• "MD2 expression is reduced in large airways of smokers and COPD smokers. ". Mol Cell Biochem. 2015. PMID 26068048.
• "Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth.". Am J Reprod Immunol. 2015. PMID 25605324.