LTBR

LTBR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1RF3, 4MXW
Dynodwyr
Cyfenwau	LTBR, CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3, lymphotoxin beta receptor
Dynodwyr allanol	OMIM: 600979 HomoloGene: 1753 GeneCards: LTBR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • tumor necrosis factor-activated receptor activity • identical protein binding • ubiquitin protein ligase binding Cydrannau o'r gell • integral component of membrane • bilen • Cellbilen • integral component of plasma membrane • Golgi apparatus Prosesau biolegol • myeloid dendritic cell differentiation • tumor necrosis factor-mediated signaling pathway • positive regulation of JNK cascade • multicellular organism development • cellular response to mechanical stimulus • response to lipopolysaccharide • regulation of cell population proliferation • positive regulation of extrinsic apoptotic signaling pathway • inflammatory response • GO:0022415 viral process • GO:0072468 signal transduction • GO:0097285 apoptotic process • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • positive regulation of I-kappaB kinase/NF-kappaB signaling • hematopoietic or lymphoid organ development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4055	n/a
Ensembl	ENSG00000111321	n/a
UniProt	P36941	n/a
RefSeq (mRNA)	NM_001270987 NM_002342	n/a
RefSeq (protein)	NP_001257916 NP_002333	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LTBR yw LTBR a elwir hefyd yn Lymphotoxin beta receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12p13.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LTBR.

• CD18
• TNFCR
• TNFR3
• D12S370
• TNFR-RP
• TNFRSF3
• TNFR2-RP
• LT-BETA-R
• TNF-R-III

Llyfryddiaeth

• "Association of LTβR gene polymorphisms with prostate volume in benign prostatic hyperplasia in the Korean population. ". Genet Mol Res. 2015. PMID 26782510.
• "Activation of lymphotoxin-beta receptor enhances the LPS-induced expression of IL-8 through NF-κB and IRF-1. ". Immunol Lett. 2015. PMID 25887375.
• "Pillars article: A lymphotoxin-B-specific receptor. Science. 1994. 264: 707-710. ". J Immunol. 2014. PMID 24563505.
• "Dimerization of LTβR by LTα1β2 is necessary and sufficient for signal transduction. ". Proc Natl Acad Sci U S A. 2013. PMID 24248355.
• "Association between lymphotoxin beta receptor gene polymorphisms and IgA nephropathy in Korean children.". Immunol Invest. 2012. PMID 22417320.