LTBP1

LTBP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1KSQ
Dynodwyr
Cyfenwau	LTBP1, latent transforming growth factor beta binding protein 1
Dynodwyr allanol	OMIM: 150390 HomoloGene: 522 GeneCards: LTBP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • calcium ion binding • transforming growth factor beta-activated receptor activity • growth factor binding • microfibril binding • transforming growth factor beta binding • extracellular matrix structural constituent Cydrannau o'r gell • GO:0005578 extracellular matrix • microfibril • extracellular space • endoplasmic reticulum lumen • extracellular region • GO:0009327 protein-containing complex • collagen-containing extracellular matrix Prosesau biolegol • ventricular septum development • sequestering of TGFbeta in extracellular matrix • coronary vasculature development • aorta development • transmembrane receptor protein serine/threonine kinase signaling pathway • post-translational protein modification • regulation of transforming growth factor beta activation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4052	n/a
Ensembl	ENSG00000049323	n/a
UniProt	Q14766	n/a
RefSeq (mRNA)	NM_000627 NM_001166264 NM_001166265 NM_001166266 NM_206943	n/a
RefSeq (protein)	NP_000618 NP_001159736 NP_001159737 NP_001159738 NP_996826	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LTBP1 yw LTBP1 a elwir hefyd yn Latent transforming growth factor beta binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p22.3.

Llyfryddiaeth

• "Latent transforming growth factor-beta binding protein-1 in circulating plasma as a novel biomarker for early detection of hepatocellular carcinoma. ". Int J Clin Exp Pathol. 2015. PMID 26884881.
• "Dental pulp stem cells suppress the proliferation of lymphocytes via transforming growth factor-β1. ". Hum Cell. 2015. PMID 25605036.
• "Cooperative effects of EGF, FGF, and TGF-β1 in prostate stromal cells are different from responses to single growth factors. ". Life Sci. 2015. PMID 25529149.
• "No association of the TGF-β1 29T/C polymorphism with breast cancer risk in Caucasian and Asian populations: evidence from a meta-analysis involving 55,841 subjects. ". Asian Pac J Cancer Prev. 2014. PMID 25374198.
• "Association of transforming growth factor-Beta 1 promoter variant -509 c/t with bronchial asthma in South Indian population.". Inflammation. 2015. PMID 25359706.