LOX

LOX
Dynodwyr
Cyfenwau	LOX, entrez:4015, lysyl oxidase, AAT10, Lysyl oxidase
Dynodwyr allanol	OMIM: 153455 HomoloGene: 1741 GeneCards: LOX
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0015922 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor • metal ion binding • GO:0001948, GO:0016582 protein binding • oxidoreductase activity • copper ion binding • protein-lysine 6-oxidase activity Cydrannau o'r gell • collagen • cnewyllyn cell • extracellular region • extracellular space • GO:0005578 extracellular matrix Prosesau biolegol • collagen fibril organization • lung development • response to steroid hormone • wound healing • aorta development • heart development • blood vessel development • response to hormone • elastic fiber assembly • blood vessel morphogenesis • peptidyl-lysine oxidation • osteoblast differentiation • regulation of protein phosphorylation • regulation of gene expression • regulation of striated muscle tissue development • regulation of transforming growth factor beta receptor signaling pathway • extracellular matrix organization • bone mineralization • platelet-derived growth factor receptor-beta signaling pathway • ascending aorta development • descending aorta development • regulation of apoptotic process • protein kinase B signaling • regulation of megakaryocyte differentiation • muscle cell cellular homeostasis • cell chemotaxis • connective tissue development • cellular response to organic substance • DNA biosynthetic process • regulation of receptor binding • regulation of bone development • cellular response to chemokine • regulation of platelet-derived growth factor receptor-beta signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4015	n/a
Ensembl	ENSG00000113083	n/a
UniProt	P28300	n/a
RefSeq (mRNA)	NM_002317 NM_001178102 NM_001317073	n/a
RefSeq (protein)	NP_001171573 NP_001304002 NP_002308	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LOX yw LOX a elwir hefyd yn Lysyl oxidase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q23.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LOX.

• AAT10

Llyfryddiaeth

• "A Novel Association between Lysyl Oxidase Gene Polymorphism and Intracranial Aneurysm in Koreans. ". Yonsei Med J. 2017. PMID 28792146.
• "Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II-induced hypertrophy. ". FASEB J. 2017. PMID 28522596.
• "Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone. ". Cancer Res. 2017. PMID 27742687.
• "Major Action of Endogenous Lysyl Oxidase in Clear Cell Renal Cell Carcinoma Progression and Collagen Stiffness Revealed by Primary Cell Cultures. ". Am J Pathol. 2016. PMID 27449199.
• "Lysyl Oxidase Gene G473A Polymorphism and Cigarette Smoking in Association with a High Risk of Lung and Colorectal Cancers in a North Chinese Population.". Int J Environ Res Public Health. 2016. PMID 27367711.