LMO4

LMO4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2L4Z
Dynodwyr
Cyfenwau	LMO4, LIM domain only 4
Dynodwyr allanol	OMIM: 603129 HomoloGene: 4927 GeneCards: LMO4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • metal ion binding • GO:0001948, GO:0016582 protein binding • GO:0001158 cis-regulatory region sequence-specific DNA binding • transcription factor binding Cydrannau o'r gell • transcription regulator complex • cell leading edge Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • ventricular septum development • spinal cord association neuron differentiation • thymus development • GO:0106160 negative regulation of protein-containing complex assembly • transcription, DNA-templated • ventral spinal cord interneuron differentiation • regulation of cell activation • spinal cord motor neuron differentiation • regulation of cell fate specification • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • neural tube closure • transcription by RNA polymerase II • positive regulation of kinase activity • regulation of cell migration Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8543	n/a
Ensembl	ENSG00000143013	n/a
UniProt	P61968	n/a
RefSeq (mRNA)	NM_006769 NM_001369491	n/a
RefSeq (protein)	NP_006760 NP_001356420	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LMO4 yw LMO4 a elwir hefyd yn LIM domain only 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p22.3.

Llyfryddiaeth

• "LMO4 expression in squamous cell carcinoma of the anterior tongue. ". Histopathology. 2011. PMID 21362019.
• "Repression of Lim only protein 4-activated transcription inhibits proliferation and induces apoptosis of normal mammary epithelial cells and breast cancer cells. ". Clin Exp Metastasis. 2010. PMID 20526802.
• "The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression. ". Respir Res. 2015. PMID 26048572.
• "The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4. ". PLoS One. 2014. PMID 25310299.
• "LMO4 is an essential cofactor in the Snail2-mediated epithelial-to-mesenchymal transition of neuroblastoma and neural crest cells.". J Neurosci. 2013. PMID 23407937.