LMAN1

LMAN1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3A4U, 3LCP, 3WHT, 3WHU, 3WNX, 4GKX, 4GKY, 4YGC, 4YGD, 4YGE, 4YGB
Dynodwyr
Cyfenwau	LMAN1, ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58, lectin, mannose binding 1
Dynodwyr allanol	OMIM: 601567 HomoloGene: 4070 GeneCards: LMAN1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • unfolded protein binding • metal ion binding • GO:0001948, GO:0016582 protein binding • mannose binding • carbohydrate binding Cydrannau o'r gell • integral component of membrane • Golgi apparatus • Golgi membrane • sarcomere • host cell perinuclear region of cytoplasm • Reticwlwm endoplasmig • ER to Golgi transport vesicle membrane • extracellular exosome • endoplasmic reticulum membrane • endoplasmic reticulum-Golgi intermediate compartment • bilen • endoplasmic reticulum-Golgi intermediate compartment membrane • COPII-coated ER to Golgi transport vesicle Prosesau biolegol • Golgi organization • early endosome to Golgi transport • blood coagulation • positive regulation of organelle organization • protein N-linked glycosylation via asparagine • COPII vesicle coating • protein exit from endoplasmic reticulum • protein folding • protein transport • vesicle-mediated transport • endoplasmic reticulum to Golgi vesicle-mediated transport • endoplasmic reticulum organization • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3998	n/a
Ensembl	ENSG00000074695	n/a
UniProt	P49257	n/a
RefSeq (mRNA)	NM_005570	n/a
RefSeq (protein)	NP_005561	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LMAN1 yw LMAN1 a elwir hefyd yn Lectin, mannose binding 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 18, band 18q21.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LMAN1.

• MR60
• gp58
• F5F8D
• FMFD1
• MCFD1
• ERGIC53
• ERGIC-53

Llyfryddiaeth

• "Mannose-binding lectin (MBL) codon 54 (rs1800450) polymorphism predisposes towards medium vessel vasculitis in patients with systemic lupus erythematosus. ". Clin Rheumatol. 2017. PMID 28097447.
• "Mannan-binding lectin reduces CpG DNA-induced inflammatory cytokine production by human monocytes. ". Microbiol Immunol. 2015. PMID 25664598.
• "The intracellular cargo receptor ERGIC-53 is required for the production of infectious arenavirus, coronavirus, and filovirus particles. ". Cell Host Microbe. 2013. PMID 24237698.
• "Two new mutations at ERGIC-53 gene in a Turkish family. ". Clin Appl Thromb Hemost. 2011. PMID 20460353.
• "High frequency of LMAN1 abnormalities in colorectal tumors with microsatellite instability.". Cancer Res. 2009. PMID 19118014.