LIN7A

LIN7A
Dynodwyr
Cyfenwau	LIN7A, LIN-7A, LIN7, MALS-1, TIP-33, VELI1, lin-7 homolog A, crumbs cell polarity complex component, MALS1
Dynodwyr allanol	OMIM: 603380 HomoloGene: 20976 GeneCards: LIN7A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • L27 domain binding Cydrannau o'r gell • postsynaptic membrane • bilen • GO:0097483, GO:0097481 postsynaptic density • cell-cell junction • bicellular tight junction • Cellbilen • cell junction • basolateral plasma membrane • neuron projection • extracellular exosome • presynapse • synapse • MPP7-DLG1-LIN7 complex • intracellular anatomical structure Prosesau biolegol • protein localization to basolateral plasma membrane • maintenance of epithelial cell apical/basal polarity • protein transport • synaptic vesicle transport • inner ear development • GO:0010554 neurotransmitter secretion • exocytosis • GO:0015915 transport • GO:0034622 protein-containing complex assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8825	n/a
Ensembl	ENSG00000111052	n/a
UniProt	O14910	n/a
RefSeq (mRNA)	NM_004664 NM_001324423	n/a
RefSeq (protein)	NP_001311352 NP_004655	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LIN7A yw LIN7A a elwir hefyd yn Lin-7 homolog A, crumbs cell polarity complex component (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q21.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LIN7A.

• LIN7
• MALS1
• VELI1
• LIN-7A
• MALS-1
• TIP-33

Llyfryddiaeth

• "Novel localisation and possible function of LIN7 and IRSp53 in mitochondria of HeLa cells. ". Eur J Cell Biol. 2016. PMID 27320196.
• "Coordinated folding and association of the LIN-2, -7 (L27) domain. An obligate heterodimerization involved in assembly of signaling and cell polarity complexes. ". J Biol Chem. 2002. PMID 12110687.
• "LIN7A is a major determinant of cell-polarity defects in breast carcinomas. ". Breast Cancer Res. 2016. PMID 26887652.
• "LIN7A depletion disrupts cerebral cortex development, contributing to intellectual disability in 12q21-deletion syndrome. ". PLoS One. 2014. PMID 24658322.
• "Differential localization of mammalian Lin-7 (MALS/Veli) PDZ proteins in the kidney.". Am J Physiol Renal Physiol. 2005. PMID 15494546.