LGALS1

LGALS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1GZW, 1W6M, 1W6N, 1W6O, 1W6P, 1W6Q, 2KM2, 2ZKN, 3OY8, 3OYW, 3T2T, 3W58, 3W59, 4XBL, 4Q27, 4Q1R, 4Q1P, 4Q2F, 4Q26, 4Y24, 4Y1Z, 4Y22, 4Y20, 4Y1U, 4Y1X, 4Y1Y, 4Y1V
Dynodwyr
Cyfenwau	LGALS1, GAL1, GBP, galectin 1
Dynodwyr allanol	OMIM: 150570 HomoloGene: 7399 GeneCards: LGALS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • lactose binding • signal transducer activity • laminin binding • carbohydrate binding • RNA binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • GO:0005578 extracellular matrix • intracellular anatomical structure • cell surface • extracellular exosome • cnewyllyn cell • extracellular space • cytosol • endoplasmic reticulum lumen • extracellular region Prosesau biolegol • negative regulation of cell-substrate adhesion • regulation of apoptotic process • negative regulation of neuron projection development • T cell costimulation • GO:1904579 cellular response to organic cyclic compound • positive regulation of viral entry into host cell • plasma cell differentiation • positive regulation of erythrocyte aggregation • response to axon injury • positive regulation of I-kappaB kinase/NF-kappaB signaling • positive regulation of dendritic cell differentiation • myoblast differentiation • cellular response to glucose stimulus • GO:0097285 apoptotic process • GO:0072468 signal transduction • response to isolation stress • post-translational protein modification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3956	n/a
Ensembl	ENSG00000100097	n/a
UniProt	P09382	n/a
RefSeq (mRNA)	NM_002305	n/a
RefSeq (protein)	NP_002296	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LGALS1 yw LGALS1 a elwir hefyd yn Galectin 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 22, band 22q13.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LGALS1.

• GBP
• GAL1

Llyfryddiaeth

• "Induction of galectin-1 by TLR-dependent PI3K activation enhances epithelial-mesenchymal transition of metastatic ovarian cancer cells. ". Oncol Rep. 2017. PMID 28350104.
• "Galectin-1 expression is associated with tumour immunity and prognosis in gingival squamous cell carcinoma. ". J Clin Pathol. 2017. PMID 28108653.
• "Systemic lupus erythematosus in the light of the regulatory effects of galectin-1 on T-cell function. ". Lupus. 2017. PMID 28100106.
• "Role of galectin-1 in urinary bladder urothelial carcinoma cell invasion through the JNK pathway. ". Cancer Sci. 2016. PMID 27440446.
• "Reversal of galectin-1 gene silencing on resistance to cisplatin in human lung adenocarcinoma A549 cells.". Biomed Pharmacother. 2016. PMID 27392028.