L1TD1

L1TD1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2LR6, 3SOO
Dynodwyr
Cyfenwau	L1TD1, ECAT11, LINE-1 type transposase domain containing 1, LINE1 type transposase domain containing 1
Dynodwyr allanol	HomoloGene: 136289 GeneCards: L1TD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • single-stranded RNA binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • ribonucleoprotein complex Prosesau biolegol • transposition, RNA-mediated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	54596	n/a
Ensembl	ENSG00000240563	n/a
UniProt	Q5T7N2	n/a
RefSeq (mRNA)	NM_019079 NM_001164835	n/a
RefSeq (protein)	NP_001158307 NP_061952	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn L1TD1 yw L1TD1 a elwir hefyd yn LINE1 type transposase domain containing 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p31.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn L1TD1.

• ECAT11

Llyfryddiaeth

• "LINE-1 hypomethylation in gastric cancer, detected by bisulfite pyrosequencing, is associated with poor prognosis. ". Gastric Cancer. 2013. PMID 23179365.
• "LINE-1 hypomethylation is associated with bladder cancer risk among nonsmoking Chinese. ". Int J Cancer. 2012. PMID 21445976.
• "Embryonic Stem Cell-Related Protein L1TD1 Is Required for Cell Viability, Neurosphere Formation, and Chemoresistance in Medulloblastoma. ". Stem Cells Dev. 2015. PMID 26159230.
• "The L1TD1 protein interactome reveals the importance of post-transcriptional regulation in human pluripotency. ". Stem Cell Reports. 2015. PMID 25702638.
• "Positive selection and multiple losses of the LINE-1-derived L1TD1 gene in mammals suggest a dual role in genome defense and pluripotency.". PLoS Genet. 2014. PMID 25211013.