KLK7

KLK7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2QXG, 2QXH, 2QXI, 2QXJ, 3BSQ
Dynodwyr
Cyfenwau	KLK7, PRSS6, SCCE, hK7, kallikrein related peptidase 7
Dynodwyr allanol	OMIM: 604438 HomoloGene: 37998 GeneCards: KLK7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0070122 peptidase activity • serine-type peptidase activity • hydrolase activity • serine-type endopeptidase activity • metalloendopeptidase activity Cydrannau o'r gell • extracellular region • epidermal lamellar body • extracellular space • secretory granule Prosesau biolegol • positive regulation of antibacterial peptide production • extracellular matrix disassembly • proteolysis • epidermis development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5650	n/a
Ensembl	ENSG00000169035	n/a
UniProt	P49862 Q6DTY1	n/a
RefSeq (mRNA)	NM_139277 NM_001207053 NM_001243126 NM_005046	n/a
RefSeq (protein)	NP_001193982 NP_001230055 NP_005037 NP_644806	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KLK7 yw KLK7 a elwir hefyd yn Kallikrein 7 splice variant 3 a Kallikrein related peptidase 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19q13.41.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KLK7.

• hK7
• SCCE
• PRSS6

Llyfryddiaeth

• "Specificity studies on Kallikrein-related peptidase 7 (KLK7) and effects of osmolytes and glycosaminoglycans on its peptidase activity. ". Biochim Biophys Acta. 2015. PMID 25448018.
• "Serum human kallikrein 7 represents a new marker for cervical cancer. ". Med Oncol. 2014. PMID 25182706.
• "Skin Barrier Function Is Not Impaired and Kallikrein 7 Gene Polymorphism Is Frequently Observed in Korean X-linked Ichthyosis Patients Diagnosed by Fluorescence in Situ Hybridization and Array Comparative Genomic Hybridization. ". J Korean Med Sci. 2016. PMID 27478344.
• "Epigenetic regulation of KLK7 gene expression in pancreatic and cervical cancer cells. ". Biol Chem. 2016. PMID 27279059.
• "Novel Biological Substrates of Human Kallikrein 7 Identified through Degradomics.". J Biol Chem. 2015. PMID 26032414.