KLC2

KLC2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3CEQ, 3EDT
Dynodwyr
Cyfenwau	KLC2, kinesin light chain 2
Dynodwyr allanol	OMIM: 611729 HomoloGene: 22468 GeneCards: KLC2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • microtubule motor activity • GO:0001948, GO:0016582 protein binding • kinesin binding • cadherin binding Cydrannau o'r gell • cytoplasm • cytosol • microtubule • Cytosgerbwd • bilen • kinesin I complex • kinesin complex • nucleoplasm • mitocondria • Cellbilen • GO:0009327 protein-containing complex Prosesau biolegol • microtubule-based movement • antigen processing and presentation of exogenous peptide antigen via MHC class II • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	64837	n/a
Ensembl	ENSG00000174996	n/a
UniProt	Q9H0B6	n/a
RefSeq (mRNA)	NM_001134774 NM_001134775 NM_001134776 NM_022822 NM_001318734	n/a
RefSeq (protein)	NP_001128246 NP_001128247 NP_001128248 NP_001305663 NP_073733	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KLC2 yw KLC2 a elwir hefyd yn Kinesin light chain 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q13.2.

Llyfryddiaeth

• "Role of kinesin light chain-2 of kinesin-1 in the traffic of Na,K-ATPase-containing vesicles in alveolar epithelial cells. ". FASEB J. 2010. PMID 19773350.
• "SRC mediates a switch from microtubule- to actin-based motility of vaccinia virus. ". Science. 2004. PMID 15297625.
• "The light chains of kinesin-1 are autoinhibited. ". Proc Natl Acad Sci U S A. 2016. PMID 26884162.
• "Overexpression of KLC2 due to a homozygous deletion in the non-coding region causes SPOAN syndrome. ". Hum Mol Genet. 2015. PMID 26385635.
• "Crystal structures of the tetratricopeptide repeat domains of kinesin light chains: insight into cargo recognition mechanisms.". PLoS One. 2012. PMID 22470497.