KIF2C

KIF2C
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2HEH, 4UBF, 4Y05
Dynodwyr
Cyfenwau	KIF2C, CT139, KNSL6, MCAK, kinesin family member 2C
Dynodwyr allanol	OMIM: 604538 HomoloGene: 21355 GeneCards: KIF2C
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • microtubule binding • microtubule plus-end binding • centromeric DNA binding • ATPase activity • GO:0001948, GO:0016582 protein binding • ATP binding • microtubule motor activity Cydrannau o'r gell • cytoplasm • bilen • kinesin complex • microtubule cytoskeleton • Cromosom • microtubule plus-end • cytoplasmic microtubule • chromosome, centromeric region • Cytosgerbwd • microtubule • cnewyllyn cell • kinetochore • nucleoplasm • centrosome • cytosol Prosesau biolegol • antigen processing and presentation of exogenous peptide antigen via MHC class II • establishment or maintenance of microtubule cytoskeleton polarity • chromosome segregation • Cellraniad • regulation of chromosome segregation • microtubule-based movement • cell cycle • microtubule depolymerization • mitotic metaphase plate congression • cell population proliferation • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • sister chromatid cohesion • metaphase plate congression • attachment of mitotic spindle microtubules to kinetochore • GO:0007067 Mitosis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11004	n/a
Ensembl	ENSG00000142945	n/a
UniProt	Q99661	n/a
RefSeq (mRNA)	NM_001297655 NM_001297656 NM_001297657 NM_006845	n/a
RefSeq (protein)	NP_001284584 NP_001284585 NP_001284586 NP_006836	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KIF2C yw KIF2C a elwir hefyd yn Kinesin-like protein KIF2C a Kinesin family member 2C (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p34.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KIF2C.

• MCAK
• CT139
• KNSL6

Llyfryddiaeth

• "Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cells. ". Cell Cycle. 2015. PMID 26148251.
• "New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C. ". J Biol Chem. 2015. PMID 26055718.
• "MCAK-mediated regulation of endothelial cell microtubule dynamics is mechanosensitive to myosin-II contractility. ". Mol Biol Cell. 2017. PMID 28298485.
• "The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition. ". Open Biol. 2016. PMID 27733589.
• "Molecular insight into the regulation and function of MCAK.". Crit Rev Biochem Mol Biol. 2015. PMID 27146484.