KIF2A

KIF2A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2GRY
Dynodwyr
Cyfenwau	KIF2A, CDCBM3, HK2, KIF2, kinesin heavy chain member 2A, kinesin family member 2A
Dynodwyr allanol	OMIM: 602591 HomoloGene: 3320 GeneCards: KIF2A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • microtubule motor activity • nucleotide binding • microtubule binding • ATPase activity • GO:0001948, GO:0016582 protein binding • cytoskeletal motor activity • ATP binding Cydrannau o'r gell • cytoplasm • cytosol • centrosome • spindle pole • bilen • kinesin complex • spindle • microtubule organizing center • sperm principal piece • spindle microtubule • nucleolus • microtubule • Cytosgerbwd • cnewyllyn cell • nuclear body • centriole • centriolar subdistal appendage Prosesau biolegol • cell differentiation • antigen processing and presentation of exogenous peptide antigen via MHC class II • GO:0043148 mitotic spindle organization • nervous system development • Cellraniad • multicellular organism development • microtubule-based movement • mitotic spindle assembly • cell cycle • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • sister chromatid cohesion • microtubule cytoskeleton organization • microtubule depolymerization • regulation of cell migration Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3796	n/a
Ensembl	ENSG00000068796	n/a
UniProt	O00139	n/a
RefSeq (mRNA)	NM_004520 NM_001098511 NM_001243952 NM_001243953	n/a
RefSeq (protein)	NP_001091981 NP_001230881 NP_001230882 NP_004511	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KIF2A yw KIF2A a elwir hefyd yn Kinesin family member 2A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q12.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KIF2A.

• HK2
• KIF2
• CDCBM3

Llyfryddiaeth

• "Kinesin Processivity Is Determined by a Kinetic Race from a Vulnerable One-Head-Bound State. ". Biophys J. 2017. PMID 28636917.
• "MLL/WDR5 Complex Regulates Kif2A Localization to Ensure Chromosome Congression and Proper Spindle Assembly during Mitosis. ". Dev Cell. 2017. PMID 28633016.
• "High KIF2A expression predicts unfavorable prognosis in diffuse large B cell lymphoma. ". Ann Hematol. 2017. PMID 28616658.
• "KIF2A Overexpression and Its Association with Clinicopathologic Characteristics and Poor Prognoses in Patients with Gastric Cancer. ". Dis Markers. 2016. PMID 27773961.
• "Role of KIF2A in the progression and metastasis of human glioma.". Mol Med Rep. 2016. PMID 26707290.