KIF1C

KIF1C
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2G1L
Dynodwyr
Cyfenwau	KIF1C, LTXS1, SATX2, SAX2, SPAX2, SPG58, kinesin family member 1C
Dynodwyr allanol	OMIM: 603060 HomoloGene: 4821 GeneCards: KIF1C
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • microtubule binding • microtubule motor activity • nucleotide binding • ATPase activity • cytoskeletal motor activity • GO:0001948, GO:0016582 protein binding • ATP binding • RNA binding • plus-end-directed microtubule motor activity Cydrannau o'r gell • cytoplasm • Golgi apparatus • microtubule • Cytosgerbwd • Reticwlwm endoplasmig • kinesin complex • axon • dendrite • neuron projection • axon cytoplasm Prosesau biolegol • cytoskeleton-dependent intracellular transport • microtubule-based movement • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • vesicle-mediated transport • anterograde neuronal dense core vesicle transport • retrograde neuronal dense core vesicle transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10749	n/a
Ensembl	ENSG00000129250	n/a
UniProt	O43896	n/a
RefSeq (mRNA)	NM_006612	n/a
RefSeq (protein)	NP_006603	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KIF1C yw KIF1C a elwir hefyd yn Kinesin family member 1C (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KIF1C.

• SAX2
• LTXS1
• SATX2
• SPAX2
• SPG58

Llyfryddiaeth

• "Directional persistence of migrating cells requires Kif1C-mediated stabilization of trailing adhesions. ". Dev Cell. 2012. PMID 23237952.
• "The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages. ". Mol Biol Cell. 2006. PMID 16554367.
• "Microtubule acetylation regulates dynamics of KIF1C-powered vesicles and contact of microtubule plus ends with podosomes. ". Eur J Cell Biol. 2014. PMID 25151635.
• "Motor protein mutations cause a new form of hereditary spastic paraplegia. ". Neurology. 2014. PMID 24808017.
• "KIF1C mutations in two families with hereditary spastic paraparesis and cerebellar dysfunction.". J Med Genet. 2014. PMID 24319291.