KCNQ4

KCNQ4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2OVC, 4GOW
Dynodwyr
Cyfenwau	KCNQ4, DFNA2, DFNA2A, KV7.4, potassium voltage-gated channel subfamily Q member 4
Dynodwyr allanol	OMIM: 603537 HomoloGene: 78107 GeneCards: KCNQ4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • potassium channel activity • voltage-gated ion channel activity • ion channel activity • GO:0001948, GO:0016582 protein binding • voltage-gated potassium channel activity • delayed rectifier potassium channel activity • calmodulin binding Cydrannau o'r gell • integral component of membrane • bilen • voltage-gated potassium channel complex • Cellbilen • basal plasma membrane Prosesau biolegol • regulation of ion transmembrane transport • cludo ïon • clyw • potassium ion transport • transmembrane transport • potassium ion transmembrane transport • inner ear morphogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9132	n/a
Ensembl	ENSG00000117013	n/a
UniProt	P56696	n/a
RefSeq (mRNA)	NM_004700 NM_172163	n/a
RefSeq (protein)	NP_004691 NP_751895	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KCNQ4 yw KCNQ4 a elwir hefyd yn Potassium voltage-gated channel subfamily Q member 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p34.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KCNQ4.

• DFNA2
• KV7.4
• DFNA2A

Llyfryddiaeth

• "KV7 channels in the human detrusor: channel modulator effects and gene and protein expression. ". Naunyn Schmiedebergs Arch Pharmacol. 2017. PMID 27761601.
• "Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection. ". Cardiovasc Res. 2016. PMID 26718475.
• "Absence of KCNQ4 mutation in Bengali families with ADNSHL originated from West Bengal, India. ". Int J Pediatr Otorhinolaryngol. 2017. PMID 28802383.
• "A novel pore-region mutation, c.887G > A (p.G296D) in KCNQ4, causing hearing loss in a Chinese family with autosomal dominant non-syndromic deafness 2. ". BMC Med Genet. 2017. PMID 28340560.
• "Synergistic interplay of Gβγ and phosphatidylinositol 4,5-bisphosphate dictates Kv7.4 channel activity.". Pflugers Arch. 2017. PMID 27981364.