KCNN2

KCNN2
Dynodwyr
Cyfenwau	KCNN2, KCa2.2, SK2, SKCA2, SKCa 2, hSK2, potassium calcium-activated channel subfamily N member 2, DYT34, NEDMAB
Dynodwyr allanol	OMIM: 605879 HomoloGene: 23150 GeneCards: KCNN2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • protein domain specific binding • calcium-activated potassium channel activity • calmodulin binding • alpha-actinin binding • GO:0001948, GO:0016582 protein binding • small conductance calcium-activated potassium channel activity Cydrannau o'r gell • integral component of membrane • bilen • cell surface • neuronal cell body • Cellbilen • Z disc • dendritic spine • neuron projection Prosesau biolegol • cludo ïon • potassium ion transport • regulation of potassium ion transmembrane transport • potassium ion transmembrane transport • membrane repolarization during atrial cardiac muscle cell action potential Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3781	n/a
Ensembl	ENSG00000080709	n/a
UniProt	Q9H2S1	n/a
RefSeq (mRNA)	NM_001278204 NM_021614 NM_170775 NM_001372233	n/a
RefSeq (protein)	NP_001265133 NP_067627 NP_740721 NP_001359162	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KCNN2 yw KCNN2 a elwir hefyd yn Potassium calcium-activated channel subfamily N member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q22.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KCNN2.

• SK2
• hSK2
• SKCA2
• KCa2.2
• SKCa*2

Llyfryddiaeth

• "KCNN2 polymorphisms and cardiac tachyarrhythmias. ". Medicine (Baltimore). 2016. PMID 27442679.
• "Small-conductance calcium-activated potassium type 2 channels (SK2, KCa2.2) in human brain. ". Brain Struct Funct. 2017. PMID 27357310.
• "Activation of SK2 channels preserves ER Ca²⁺ homeostasis and protects against ER stress-induced cell death. ". Cell Death Differ. 2016. PMID 26586570.
• "Heterogeneous upregulation of apamin-sensitive potassium currents in failing human ventricles. ". J Am Heart Assoc. 2013. PMID 23525437.
• "Cell-cycle-dependent regulation of Ca2+-activated K+ channel in Jurkat T-lymphocyte.". J Pharmacol Sci. 2007. PMID 17452806.