KCNMB2

KCNMB2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1JO6
Dynodwyr
Cyfenwau	KCNMB2, potassium calcium-activated channel subfamily M regulatory beta subunit 2
Dynodwyr allanol	OMIM: 605214 HomoloGene: 4257 GeneCards: KCNMB2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • potassium channel regulator activity • calcium-activated potassium channel activity • ion channel inhibitor activity Cydrannau o'r gell • integral component of membrane • voltage-gated potassium channel complex • Cellbilen • integral component of plasma membrane • bilen Prosesau biolegol • detection of calcium ion • action potential • potassium ion transport • regulation of vasoconstriction • cludo ïon • neuronal action potential • chemical synaptic transmission • potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10242	n/a
Ensembl	ENSG00000197584	n/a
UniProt	Q9Y691	n/a
RefSeq (mRNA)	NM_001278911 NM_005832 NM_181361	n/a
RefSeq (protein)	NP_001265840 NP_005823 NP_852006	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KCNMB2 yw KCNMB2 a elwir hefyd yn Potassium calcium-activated channel subfamily M regulatory beta subunit 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3q26.32.

Llyfryddiaeth

• "Endocytic trafficking signals in KCNMB2 regulate surface expression of a large conductance voltage and Ca(2+)-activated K+ channel. ". Neuroscience. 2007. PMID 17521822.
• "BK channels with beta3a subunits generate use-dependent slow afterhyperpolarizing currents by an inactivation-coupled mechanism. ". J Neurosci. 2007. PMID 17460083.
• "Novel spliced variants of large-conductance Ca(2+)-activated K(+)-channel β2-subunit in human and rodent pancreas. ". J Pharmacol Sci. 2010. PMID 20859064.
• "Inactivation of BK channels by the NH2 terminus of the beta2 auxiliary subunit: an essential role of a terminal peptide segment of three hydrophobic residues. ". J Gen Physiol. 2003. PMID 12566540.
• "NMR structure of the "ball-and-chain" domain of KCNMB2, the beta 2-subunit of large conductance Ca2+- and voltage-activated potassium channels.". J Biol Chem. 2001. PMID 11517232.