KCNAB2

KCNAB2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ZSX
Dynodwyr
Cyfenwau	KCNAB2, AKR6A5, HKvbeta2, HKvbeta2.1, HKvbeta2.2, KCNA2B, KV-BETA-2, potassium voltage-gated channel subfamily A regulatory beta subunit 2
Dynodwyr allanol	OMIM: 601142 HomoloGene: 56492 GeneCards: KCNAB2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • aldo-keto reductase (NADP) activity • voltage-gated ion channel activity • potassium channel regulator activity • voltage-gated potassium channel activity • oxidoreductase activity Cydrannau o'r gell • axon terminus • cytoplasm • integral component of membrane • cytosol • cell projection • bilen • GO:0097483, GO:0097481 postsynaptic density • extrinsic component of cytoplasmic side of plasma membrane • voltage-gated potassium channel complex • Cellbilen • synapse • axon • cell junction • pinceau fiber • neuron projection • microtubule • Cytosgerbwd • juxtaparanode region of axon • specific granule membrane • tertiary granule membrane Prosesau biolegol • NADPH oxidation • regulation of protein localization to cell surface • regulation of ion transmembrane transport • cludo ïon • potassium ion transport • neuromuscular process • hematopoietic progenitor cell differentiation • potassium ion transmembrane transport • regulation of potassium ion transmembrane transport • neutrophil degranulation • cludo transmembrane rhwng ïonau Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8514	n/a
Ensembl	ENSG00000069424	n/a
UniProt	Q13303	n/a
RefSeq (mRNA)	NM_001199860 NM_001199861 NM_001199862 NM_001199863 NM_003636 NM_172130	n/a
RefSeq (protein)	NP_001186789 NP_001186790 NP_001186791 NP_001186792 NP_003627 NP_742128 NP_001186789.1 NP_001186790.1 NP_003627.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KCNAB2 yw KCNAB2 a elwir hefyd yn Voltage-gated potassium channel subunit beta-2 a Potassium voltage-gated channel, shaker-related subfamily, beta member 2, isoform CRA_a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p36.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KCNAB2.

• AKR6A5
• KCNA2B
• HKvbeta2
• KV-BETA-2
• HKvbeta2.1
• HKvbeta2.2

Llyfryddiaeth

• "Shaker K+ channel beta subunits belong to an NAD(P)H-dependent oxidoreductase superfamily. ". Cell. 1994. PMID 8001150.
• "Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation. ". Eur Heart J. 2013. PMID 23264583.
• "Dysfunction of the Voltage-Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome. ". J Am Heart Assoc. 2016. PMID 27287695.
• "Molecular basis of transient outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density. ". Circulation. 1998. PMID 9760292.
• "Localization of two potassium channel beta subunit genes, KCNA1B and KCNA2B.". Genomics. 1996. PMID 8838324.