KCNA3

KCNA3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4BGC
Dynodwyr
Cyfenwau	KCNA3, HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3, potassium voltage-gated channel subfamily A member 3
Dynodwyr allanol	OMIM: 176263 HomoloGene: 128570 GeneCards: KCNA3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • outward rectifier potassium channel activity • potassium channel activity • voltage-gated ion channel activity • ion channel activity • voltage-gated potassium channel activity • delayed rectifier potassium channel activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • bilen • voltage-gated potassium channel complex • Cellbilen • integral component of plasma membrane • axon • membrane raft • integral component of membrane • calyx of Held • glutamatergic synapse • integral component of postsynaptic membrane • integral component of presynaptic membrane Prosesau biolegol • regulation of ion transmembrane transport • cludo ïon • potassium ion transport • transmembrane transport • protein homooligomerization • potassium ion transmembrane transport • potassium ion export across plasma membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3738	n/a
Ensembl	ENSG00000177272	n/a
UniProt	P22001	n/a
RefSeq (mRNA)	NM_002232	n/a
RefSeq (protein)	NP_002223	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KCNA3 yw KCNA3 a elwir hefyd yn Potassium voltage-gated channel subfamily A member 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KCNA3.

• MK3
• HGK5
• HLK3
• PCN3
• HPCN3
• KV1.3
• HUKIII

Llyfryddiaeth

• "Molecular Determinants of Kv1.3 Potassium Channels-induced Proliferation. ". J Biol Chem. 2016. PMID 26655221.
• "The voltage-gated potassium channel Kv1.3 is a promising multitherapeutic target against human pathologies. ". Expert Opin Ther Targets. 2016. PMID 26634786.
• "Biophysical characterization and expression analysis of Kv1.3 potassium channel in primary human leukemic B cells. ". Cell Physiol Biochem. 2015. PMID 26393354.
• "Human α-defensins are immune-related Kv1.3 channel inhibitors: new support for their roles in adaptive immunity. ". FASEB J. 2015. PMID 26148969.
• "Inhibition of Kv1.3 Channels in Human Jurkat T Cells by Xanthohumol and Isoxanthohumol.". J Membr Biol. 2015. PMID 25688010.