KAT2B Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1CM0 , 1JM4 , 1N72 , 1WUG , 1WUM , 1ZS5 , 2RNW , 2RNX , 3GG3 , 4NSQ , 5FE2 , 5FE4 , 5FDZ , 5FE8 , 5FE5 , 5FE1 , 5FE7 , 5FE9 , 5FE3 , 5FE0 , 5FE6
Dynodwyr Cyfenwau KAT2B Dynodwyr allanol OMIM: 602303 HomoloGene: 20834 GeneCards: KAT2B Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001104 transcription coregulator activity • GO:0001948, GO:0016582 protein binding • acyltransferase activity • histone acetyltransferase activity • cyclin-dependent protein serine/threonine kinase inhibitor activity • protein kinase binding • chromatin binding • lysine N-acetyltransferase activity, acting on acetyl phosphate as donor • GO:0001105 transcription coactivator activity • transcription factor binding • histone deacetylase binding • acetyltransferase activity • GO:0032403 protein-containing complex binding • peptide-lysine-N-acetyltransferase activity • diamine N-acetyltransferase activity Cydrannau o'r gell • I band • nucleoplasm • histone acetyltransferase complex • A band • actomyosin • kinetochore • cnewyllyn cell • cytoplasm • centrosome • microtubule organizing center • Cytosgerbwd • GO:0009327 protein-containing complex Prosesau biolegol • Notch signaling pathway • regulation of protein ADP-ribosylation • epigenetic maintenance of chromatin in transcription-competent conformation • chromatin remodeling • GO:0009373 regulation of transcription, DNA-templated • negative regulation of cyclin-dependent protein serine/threonine kinase activity • proses rythmig • N-terminal peptidyl-lysine acetylation • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • histone acetylation • histone H3 acetylation • cellular response to insulin stimulus • histone H3-K9 acetylation • cell cycle • transcription initiation from RNA polymerase II promoter • GO:0022415 viral process • peptidyl-lysine acetylation • negative regulation of cell population proliferation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • internal peptidyl-lysine acetylation • regulation of megakaryocyte differentiation • protein acetylation • positive regulation of transcription of Notch receptor target • heart development • positive regulation of Notch signaling pathway • negative regulation of centriole replication • limb development • protein deubiquitination Sources:Amigo / QuickGO
Orthologau Species Bod dynol Llygoden Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Lleoliad (UCSC) n/a n/a PubMed search[1] n/a Wicidata
Protein sy'n cael ei godio yn y corff dynol gan y genyn KAT2B yw KAT2B a elwir hefyd yn Lysine acetyltransferase 2B (Saesneg). Segment o DNA yw'r genyn , sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p24.3.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KAT2B.
"Histone Acetyltransferase p300/CREB-binding Protein-associated Factor (PCAF) Is Required for All-trans-retinoic Acid-induced Granulocytic Differentiation in Leukemia Cells. ". J Biol Chem . 2017. PMID 28053092 . "P300/CBP-associated factor (PCAF) inhibits the growth of hepatocellular carcinoma by promoting cell autophagy. ". Cell Death Dis . 2016. PMID 27711074 . "Competitive Inhibition of Lysine Acetyltransferase 2B by a Small Motif of the Adenoviral Oncoprotein E1A. ". J Biol Chem . 2016. PMID 27143356 . "Acetylation regulates DNA repair mechanisms in human cells. ". Cell Cycle . 2016. PMID 27104361 . "Sharon Dent: The unfolding SAGA of chromatin-modifying proteins. ". J Cell Biol . 2016. PMID 26728851 . 
