ITGAX

ITGAX
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1N3Y, 2LUV, 3K6S, 3K71, 3K72, 4NEH, 4NEN, 5ES4
Dynodwyr
Cyfenwau	ITGAX, CD11C, SLEB6, integrin subunit alpha X
Dynodwyr allanol	OMIM: 151510 HomoloGene: 55493 GeneCards: ITGAX
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • metal ion binding • signaling receptor activity Cydrannau o'r gell • integral component of membrane • cell surface • integrin complex • Cellbilen • bilen • secretory granule membrane • tertiary granule membrane • ficolin-1-rich granule membrane Prosesau biolegol • animal organ morphogenesis • integrin-mediated signaling pathway • heterotypic cell-cell adhesion • cell adhesion • extracellular matrix organization • leukocyte migration • positive regulation of protein targeting to mitochondrion • neutrophil degranulation • cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3687	n/a
Ensembl	ENSG00000140678	n/a
UniProt	P20702	n/a
RefSeq (mRNA)	NM_000887 NM_001286375	n/a
RefSeq (protein)	NP_000878 NP_001273304	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ITGAX yw ITGAX a elwir hefyd yn Integrin subunit alpha X (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ITGAX.

• CD11C
• SLEB6

Llyfryddiaeth

• "CD11c expression in chronic lymphocytic leukemia revisited, related with complications and survival. ". Int J Lab Hematol. 2017. PMID 28603911.
• "CD11c is upregulated in CD8+ T cells of patients with Behçet's disease. ". Clin Exp Rheumatol. 2016. PMID 27309860.
• "[The number of peripheral blood CD11c+ antigen presenting cells increases and their function strengthens in the patients with active pulmonary tuberculosis]. ". Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2016. PMID 26927560.
• "High expression of CD11c indicates favorable prognosis in patients with gastric cancer. ". World J Gastroenterol. 2015. PMID 26309367.
• "Expression of CD11c in periprosthetic tissues from failed total hip arthroplasties.". J Biomed Mater Res A. 2016. PMID 26255872.