IST1

IST1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3FRR, 3FRS, 4U7E, 4U7I, 4U7Y, 4WZX, 3JC1
Dynodwyr
Cyfenwau	IST1, OLC1, KIAA0174, ESCRT-III associated factor, CHMP8, IST1 factor associated with ESCRT-III
Dynodwyr allanol	OMIM: 616434 HomoloGene: 8849 GeneCards: IST1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein domain specific binding • GO:0032403 protein-containing complex binding • GO:0001948, GO:0016582 protein binding • MIT domain binding • cadherin binding Cydrannau o'r gell • cytoplasm • cytosol • centrosome • Flemming body • microtubule organizing center • extracellular exosome • Cytosgerbwd • GO:0016023 cytoplasmic vesicle • endoplasmic reticulum-Golgi intermediate compartment • midbody • nuclear envelope • cnewyllyn cell • extracellular region • azurophil granule lumen • intracellular membrane-bounded organelle • chromatin Prosesau biolegol • GO:0034613 protein localization • viral release from host cell • abscission • establishment of protein localization • viral capsid secondary envelopment • multivesicular body assembly • cytokinesis • positive regulation of collateral sprouting • Cellraniad • positive regulation of proteolysis • protein transport • cell cycle • ESCRT III complex disassembly • neutrophil degranulation • cytoskeleton-dependent cytokinesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9798	n/a
Ensembl	ENSG00000182149	n/a
UniProt	P53990	n/a
RefSeq (mRNA)	NM_014761 NM_001270975 NM_001270976 NM_001270977 NM_001270978 NM_001270979	n/a
RefSeq (protein)	NP_001257904 NP_001257905 NP_001257906 NP_001257907 NP_001257908 NP_055576	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IST1 yw IST1 a elwir hefyd yn IST1, ESCRT-III associated factor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16q22.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IST1.

• OLC1

Llyfryddiaeth

• "Over-expression of the overexpressed in lung cancer-1 is associated with poor prognosis in colorectal cancer. ". Anticancer Res. 2014. PMID 24403489.
• "Over-expression of the overexpressed in lung cancer 1 is associated with poor prognosis in epithelial ovarian cancer. ". J Surg Oncol. 2013. PMID 23609236.
• "[Overexpression of OLC1 in Lung Squamous Cell Carcinoma Tissues is Associated with Poor Prognosis of Patients]. ". Zhongguo Fei Ai Za Zhi. 2017. PMID 28532543.
• "OLC1 is overexpressed in breast cancer and its expression correlates with poor patient survival. ". Tumour Biol. 2014. PMID 24880589.
• "Overexpression of OLC1 promotes tumorigenesis of human esophageal squamous cell carcinoma.". PLoS One. 2014. PMID 24608342.