INPP5B

INPP5B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3MTC, 3N9V, 4CML, 5A7J, 5A7I
Dynodwyr
Cyfenwau	INPP5B, 5PTase, inositol polyphosphate-5-phosphatase B
Dynodwyr allanol	OMIM: 147264 HomoloGene: 69021 GeneCards: INPP5B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity • GO:0001948, GO:0016582 protein binding • hydrolase activity • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • inositol-1,4,5-trisphosphate 5-phosphatase activity • inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity • inositol phosphate phosphatase activity Cydrannau o'r gell • integral component of membrane • cytosol • endosome • phagocytic vesicle membrane • Golgi apparatus • early endosome membrane • bilen • Cellbilen • GO:0016023 cytoplasmic vesicle • endoplasmic reticulum-Golgi intermediate compartment • cytoplasm Prosesau biolegol • flagellated sperm motility • in utero embryonic development • inositol phosphate metabolic process • regulation of protein processing • phosphatidylinositol dephosphorylation • spermatogenesis • regulation of small GTPase mediated signal transduction • GO:0072468 signal transduction • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • inositol phosphate dephosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3633	n/a
Ensembl	ENSG00000204084	n/a
UniProt	P32019	n/a
RefSeq (mRNA)	NM_001297434 NM_005540 NM_001350227 NM_001350228	n/a
RefSeq (protein)	NP_001284363 NP_005531 NP_001337156 NP_001337157 NP_001352749 NP_001352750 NP_001352751 NP_001352752 NP_001352753 NP_001352754	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn INPP5B yw INPP5B a elwir hefyd yn Inositol polyphosphate-5-phosphatase B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p34.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn INPP5B.

• 5PTase

Llyfryddiaeth

• "Identification of inhibitors of inositol 5-phosphatases through multiple screening strategies. ". ACS Chem Biol. 2014. PMID 24742366.
• "Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. ". Mol Biol Cell. 2012. PMID 22072788.
• "Targeting of the type II inositol polyphosphate 5-phosphatase INPP5B to the early secretory pathway. ". J Cell Sci. 2007. PMID 17956944.
• "Tissue distribution and intracellular localisation of the 75-kDa inositol polyphosphate 5-phosphatase. ". Eur J Biochem. 1995. PMID 8529643.
• "Localization of the 75-kDa inositol polyphosphate-5-phosphatase (INPP5B) to human chromosome band 1p34.". Cytogenet Cell Genet. 1994. PMID 8125013.