ING2

ING2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WES, 2G6Q
Dynodwyr
Cyfenwau	ING2, ING1L, p33inhibitor of growth family member 2
Dynodwyr allanol	OMIM: 604215 HomoloGene: 20388 GeneCards: ING2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • chromatin binding • metal ion binding • methylated histone binding • GO:0001948, GO:0016582 protein binding • phosphatidylinositol binding • GO:0032403 protein-containing complex binding Cydrannau o'r gell • Golgi apparatus • Cellbilen • Sin3 complex • CCAAT-binding factor complex • cnewyllyn cell • nucleoplasm • cytosol Prosesau biolegol • flagellated sperm motility • positive regulation of transforming growth factor beta receptor signaling pathway • GO:0009373 regulation of transcription, DNA-templated • negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator • negative regulation of apoptotic signaling pathway • male meiosis I • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • male germ-line stem cell asymmetric division • seminiferous tubule development • spermatogenesis • spermatid development • regulation of growth • regulation of response to DNA damage stimulus • GO:0072468 signal transduction • negative regulation of cell population proliferation • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization • positive regulation of histone deacetylation • regulation of apoptotic process • regulation of cellular senescence Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3622	n/a
Ensembl	ENSG00000168556	n/a
UniProt	Q9H160	n/a
RefSeq (mRNA)	NM_001291959 NM_001564	n/a
RefSeq (protein)	NP_001278888 NP_001555	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ING2 yw ING2 a elwir hefyd yn Inhibitor of growth family member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q35.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ING2.

• ING1L
• p33ING2

Llyfryddiaeth

• "A novel tumor suppressor gene in basal cell carcinoma: inhibition of growth factor-2. ". Tumour Biol. 2015. PMID 25613071.
• "Nuclear ING2 expression is reduced in osteosarcoma. ". Oncol Rep. 2014. PMID 25190103.
• "Decreased expression of ING2 gene and its clinicopathological significance in Chinese NSCLC patients. ". Neoplasma. 2014. PMID 24712846.
• "Knockdown of inhibitor of growth protein 2 inhibits cell invasion and enhances chemosensitivity to 5-FU in human gastric cancer cells. ". Dig Dis Sci. 2013. PMID 23864195.
• "Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damage.". Sci Rep. 2013. PMID 23823870.