IMPA1

IMPA1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1AWB, 1IMA, 1IMB, 1IMC, 1IMD, 1IME, 1IMF, 2HHM, 4AS4
Dynodwyr
Cyfenwau	IMPA1, IMP, IMPA, inositol monophosphatase 1, MRT59
Dynodwyr allanol	OMIM: 602064 HomoloGene: 4043 GeneCards: IMPA1
EC number	3.1.3.94
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • inositol monophosphate phosphatase activity • manganese ion binding • protein homodimerization activity • metal ion binding • lithium ion binding • GO:0001948, GO:0016582 protein binding • identical protein binding • hydrolase activity • magnesium ion binding • inositol monophosphate 1-phosphatase activity • inositol monophosphate 4-phosphatase activity • inositol monophosphate 3-phosphatase activity Cydrannau o'r gell • cytoplasm • cytosol Prosesau biolegol • inositol metabolic process • inositol biosynthetic process • inositol phosphate metabolic process • phosphatidylinositol phosphate biosynthetic process • phosphate-containing compound metabolic process • phosphatidylinositol biosynthetic process • GO:0072468 signal transduction • inositol phosphate dephosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3612	n/a
Ensembl	ENSG00000133731	n/a
UniProt	P29218	n/a
RefSeq (mRNA)	NM_005536 NM_001144878 NM_001144879	n/a
RefSeq (protein)	NP_001138350 NP_001138351 NP_005527	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IMPA1 yw IMPA1 a elwir hefyd yn Inositol monophosphatase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q21.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IMPA1.

• IMP
• IMPA
• MRT59

Llyfryddiaeth

• "A homozygous loss-of-function mutation in inositol monophosphatase 1 (IMPA1) causes severe intellectual disability. ". Mol Psychiatry. 2016. PMID 26416544.
• "Inositol monophosphatase activity in normal, Down syndrome and dementia of the Alzheimer type CSF. ". Neurobiol Aging. 2002. PMID 11959401.
• "Production of monoclonal antibodies and immunohistochemical studies of brain myo-inositol monophosphate phosphatase. ". Mol Cells. 2002. PMID 11911470.
• "Effect of bipolar disorder on lymphocyte inositol monophosphatase mRNA levels. ". Int J Neuropsychopharmacol. 1999. PMID 11281967.
• "Genomic structure and chromosomal localization of a human myo-inositol monophosphatase gene (IMPA).". Genomics. 1997. PMID 9339367.