IL4R

IL4R
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1IAR, 1IRS, 3BPL, 3BPN, 3BPO, 5E4E
Dynodwyr
Cyfenwau	IL4R, CD124, IL-4RA, IL4RA, Interleukin-4 receptor, interleukin 4 receptor
Dynodwyr allanol	OMIM: 147781 HomoloGene: 7784 GeneCards: IL4R
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • GO:0016518 cytokine receptor activity • interleukin-4 receptor activity Cydrannau o'r gell • integral component of membrane • bilen • receptor complex • integral component of plasma membrane • extracellular region • extracellular space • Cellbilen Prosesau biolegol • immune system process • positive regulation of immunoglobulin production • positive regulation of macrophage activation • positive regulation of mast cell degranulation • response to estrogen • production of molecular mediator involved in inflammatory response • positive regulation of myoblast fusion • negative regulation of T-helper 1 cell differentiation • regulation of cell population proliferation • immunoglobulin mediated immune response • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • positive regulation of T-helper 2 cell differentiation • ovulation • GO:0072468 signal transduction • defense response to protozoan • interleukin-4-mediated signaling pathway • response to odorant • cytokine-mediated signaling pathway • positive regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3566	n/a
Ensembl	ENSG00000077238	n/a
UniProt	P24394	n/a
RefSeq (mRNA)	NM_000418 NM_001008699 NM_001257406 NM_001257407 NM_001257997	n/a
RefSeq (protein)	NP_000409 NP_001244335 NP_001244336 NP_001244926	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IL4R yw IL4R a elwir hefyd yn Interleukin-4 receptor subunit alpha ac Interleukin 4 receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p12.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IL4R.

• CD124
• IL4RA
• IL-4RA

Llyfryddiaeth

• "[Correlations of IL-4R gene polymorphism and serum IgE levels with asthma predictive index]. ". Zhongguo Dang Dai Er Ke Za Zhi. 2015. PMID 26695670.
• "Essential role of endocytosis for interleukin-4-receptor-mediated JAK/STAT signalling. ". J Cell Sci. 2015. PMID 26306492.
• "Association of the IL-4R Q576R polymorphism and asthma in the Chinese Han population: a meta-analysis. ". Genet Mol Res. 2015. PMID 25867440.
• "Dynamics and interaction of interleukin-4 receptor subunits in living cells. ". Biophys J. 2014. PMID 25468331.
• "rs1801275 Interleukin-4 receptor alpha polymorphism in familial hypercholesterolemia.". J Clin Lipidol. 2014. PMID 25110223.