IL2RB

IL2RB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2B5I, 2ERJ, 3QAZ, 4GS7
Dynodwyr
Cyfenwau	IL2RB, CD122, IL15RB, P70-75, interleukin 2 receptor subunit beta, IMD63
Dynodwyr allanol	OMIM: 146710 HomoloGene: 47955 GeneCards: IL2RB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • interleukin-2 binding • GO:0001948, GO:0016582 protein binding • GO:0016518 cytokine receptor activity • interleukin-2 receptor activity • interleukin-15 receptor activity Cydrannau o'r gell • integral component of membrane • bilen • Cellbilen • integral component of plasma membrane • external side of plasma membrane • endosome • cytosol • interleukin-2 receptor complex • cell surface Prosesau biolegol • negative regulation of apoptotic process • MAPK cascade • interleukin-2-mediated signaling pathway • GO:0022415 viral process • GO:0072468 signal transduction • cytokine-mediated signaling pathway • interleukin-15-mediated signaling pathway • regulation of molecular function • positive regulation of phagocytosis • GO:0034622 protein-containing complex assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3560	n/a
Ensembl	ENSG00000100385	n/a
UniProt	P14784	n/a
RefSeq (mRNA)	NM_000878 NM_001346222 NM_001346223	n/a
RefSeq (protein)	NP_000869 NP_001333151 NP_001333152	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IL2RB yw IL2RB a elwir hefyd yn Interleukin 2 receptor subunit beta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q12.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IL2RB.

• CD122
• IL15RB
• P70-75

Llyfryddiaeth

• "Abnormal expression pattern of the IL-2 receptor β-chain on CD4+ T cells in ANCA-associated vasculitis. ". Dis Markers. 2014. PMID 24648606.
• "Oxalate upregulates expression of IL-2Rβ and activates IL-2R signaling in HK-2 cells, a line of human renal epithelial cells. ". Am J Physiol Renal Physiol. 2014. PMID 24523387.
• "Neutrality of miniSTR D22S1045 marker by Ewing's sarcoma phenotype. ". Leg Med (Tokyo). 2013. PMID 24112992.
• "Ectodomain shedding of interleukin-2 receptor beta and generation of an intracellular functional fragment. ". J Biol Chem. 2010. PMID 20495002.
• "Interleukin-2 receptor beta gene C627T polymorphism in Korean women with endometriosis: a case-control study.". Hum Reprod. 2009. PMID 19602517.