IGFBP6

IGFBP6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1RMJ
Dynodwyr
Cyfenwau	IGFBP6, IBP6, insulin like growth factor binding protein 6
Dynodwyr allanol	OMIM: 146735 HomoloGene: 1641 GeneCards: IGFBP6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • insulin-like growth factor binding • signaling receptor binding • growth factor binding • insulin-like growth factor I binding • insulin-like growth factor II binding • fibronectin binding Cydrannau o'r gell • cytoplasm • Golgi apparatus • extracellular region • extracellular space • insulin-like growth factor binary complex Prosesau biolegol • regulation of insulin-like growth factor receptor signaling pathway • negative regulation of canonical Wnt signaling pathway • regulation of cell growth • GO:0072468 signal transduction • negative regulation of cell population proliferation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3489	n/a
Ensembl	n/a	n/a
UniProt	P24592	n/a
RefSeq (mRNA)	NM_002178	n/a
RefSeq (protein)	NP_002169	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IGFBP6 yw IGFBP6 a elwir hefyd yn Insulin like growth factor binding protein 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q13.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IGFBP6.

• IBP6

Llyfryddiaeth

• "Downregulation of Insulin-like growth factor binding protein 6 is associated with ACTH-secreting pituitary adenoma growth. ". Pituitary. 2014. PMID 24379119.
• "Insulin-like growth factor-binding protein-6 and cancer. ". Clin Sci (Lond). 2013. PMID 23126425.
• "Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts. ". Mech Ageing Dev. 2011. PMID 21820463.
• "A novel interaction between insulin-like growth factor binding protein-6 and the vitamin D receptor inhibits the role of vitamin D3 in osteoblast differentiation. ". Mol Cell Endocrinol. 2011. PMID 21458526.
• "Cross-talk between MAP kinase pathways is involved in IGF-independent, IGFBP-6-induced Rh30 rhabdomyosarcoma cell migration.". J Cell Physiol. 2010. PMID 20432455.