IGF2BP3

IGF2BP3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2E44
Dynodwyr
Cyfenwau	IGF2BP3, CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3, insulin like growth factor 2 mRNA binding protein 3
Dynodwyr allanol	OMIM: 608259 HomoloGene: 4773 GeneCards: IGF2BP3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • mRNA 5'-UTR binding • GO:0001948, GO:0016582 protein binding • translation regulator activity • mRNA 3'-UTR binding • nucleic acid binding • RNA binding Cydrannau o'r gell • cnewyllyn cell • cytoplasm • cytosol Prosesau biolegol • anatomical structure morphogenesis • negative regulation of translation • mRNA transport • protein biosynthesis • regulation of translation • regulation of mRNA stability • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10643	n/a
Ensembl	ENSG00000136231	n/a
UniProt	O00425	n/a
RefSeq (mRNA)	NM_006547	n/a
RefSeq (protein)	NP_006538	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IGF2BP3 yw IGF2BP3 a elwir hefyd yn Insulin like growth factor 2 mRNA binding protein 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p15.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IGF2BP3.

• KOC
• CT98
• IMP3
• KOC1
• IMP-3
• VICKZ3

Llyfryddiaeth

• "Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is a marker that predicts presence of invasion in papillary biliary tumors. ". Hum Pathol. 2017. PMID 28089541.
• "IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC. ". Cell Rep. 2016. PMID 27210763.
• "Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition. ". J Clin Invest. 2017. PMID 28481226.
• "Expression profile, clinical significance, and biological function of insulin-like growth factor 2 messenger RNA-binding proteins in non-small cell lung cancer. ". Tumour Biol. 2017. PMID 28381175.
• "IMP3 Expression in Borderline Tumors of the Ovary.". Anticancer Res. 2017. PMID 28179304.