IGF2BP2

IGF2BP2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CQH
Dynodwyr
Cyfenwau	IGF2BP2, IMP-2, IMP2, VICKZ2, insulin like growth factor 2 mRNA binding protein 2
Dynodwyr allanol	OMIM: 608289 HomoloGene: 4774 GeneCards: IGF2BP2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • mRNA 5'-UTR binding • GO:0001948, GO:0016582 protein binding • mRNA binding • translation regulator activity • mRNA 3'-UTR binding • nucleic acid binding • RNA binding Cydrannau o'r gell • cytoplasm • Cytosgerbwd • cnewyllyn cell • cytosol Prosesau biolegol • anatomical structure morphogenesis • negative regulation of translation • mRNA transport • regulation of translation • regulation of mRNA stability • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10644	n/a
Ensembl	ENSG00000073792	n/a
UniProt	Q9Y6M1	n/a
RefSeq (mRNA)	NM_001007225 NM_001291869 NM_001291872 NM_001291873 NM_001291874 NM_001291875 NM_006548	n/a
RefSeq (protein)	NP_001007226 NP_001278798 NP_001278801 NP_001278802 NP_001278803 NP_001278804 NP_006539	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IGF2BP2 yw IGF2BP2 a elwir hefyd yn Insulin like growth factor 2 mRNA binding protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q27.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IGF2BP2.

• IMP2
• IMP-2
• VICKZ2

Llyfryddiaeth

• "Autoimmune Response to IGF2 mRNA-Binding Protein 2 (IMP2/p62) in Breast Cancer. ". Scand J Immunol. 2015. PMID 25721883.
• "Correlation between IGF2BP2 gene polymorphism and the risk of breast cancer in Chinese Han women. ". Biomed Pharmacother. 2015. PMID 25661373.
• "Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations. ". Diabetes. 2016. PMID 27625022.
• "Association between IGF2BP2 Polymorphisms and Type 2 Diabetes Mellitus: A Case-Control Study and Meta-Analysis. ". Int J Environ Res Public Health. 2016. PMID 27294943.
• "p62/IMP2 stimulates cell migration and reduces cell adhesion in breast cancer.". Oncotarget. 2015. PMID 26416451.