IFNGR1

IFNGR1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1FG9, 1FYH, 1JRH
Dynodwyr
Cyfenwau	IFNGR1, CD119, IFNGR, IMD27A, IMD27B, interferon gamma receptor 1
Dynodwyr allanol	OMIM: 107470 HomoloGene: 359 GeneCards: IFNGR1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • interferon-gamma receptor activity • GO:0001948, GO:0016582 protein binding • GO:0019974 cytokine binding • GO:0016518 cytokine receptor activity Cydrannau o'r gell • integral component of membrane • integral component of plasma membrane • bilen • Cellbilen Prosesau biolegol • response to virus • regulation of interferon-gamma-mediated signaling pathway • GO:0072468 signal transduction • interferon-gamma-mediated signaling pathway • cytokine-mediated signaling pathway • microglial cell activation • GO:1901313 positive regulation of gene expression • astrocyte activation • negative regulation of amyloid-beta clearance • positive regulation of amyloid-beta formation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3459	n/a
Ensembl	ENSG00000027697	n/a
UniProt	P15260	n/a
RefSeq (mRNA)	NM_000416 NM_001363526 NM_001363527	n/a
RefSeq (protein)	NP_000407 NP_001350455 NP_001350456	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IFNGR1 yw IFNGR1 a elwir hefyd yn Interferon gamma receptor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IFNGR1.

• CD119
• IFNGR
• IMD27A
• IMD27B

Llyfryddiaeth

• "Association of Interferon-γReceptor-1 Gene Polymorphism with Nontuberculous Mycobacterial Lung Infection among Iranian Patients with Pulmonary Disease. ". Am J Trop Med Hyg. 2017. PMID 28719321.
• "Missense splice variant (g.20746A>G, p.Ile183Val) of interferon gamma receptor 1 (IFNGR1) coincidental with mycobacterial osteomyelitis - a screen of osteoarticular lesions. ". Bosn J Basic Med Sci. 2016. PMID 27356097.
• "Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum. ". J Allergy Clin Immunol. 2015. PMID 26343451.
• "[Disseminated BCG disease revealing a partial deficiency in receptor 1 interferon gamma]. ". Arch Pediatr. 2015. PMID 26251056.
• "Association between interferon gamma receptor 1-56C/T gene polymorphism and tuberculosis susceptibility: a meta-analysis.". Chin Med J (Engl). 2014. PMID 25382336.