IFNAR2

IFNAR2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1N6U, 1N6V, 2HYM, 2KZ1, 2LAG, 3S8W, 3S9D, 3SE3, 3SE4
Dynodwyr
Cyfenwau	IFNAR2, IFN-R, IFN-alpha-REC, IFNABR, IFNARB, IMD45, interferon alpha and beta receptor subunit 2
Dynodwyr allanol	OMIM: 602376 HomoloGene: 49242 GeneCards: IFNAR2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • type I interferon binding • protein kinase binding • type I interferon receptor activity • GO:0016518 cytokine receptor activity Cydrannau o'r gell • integral component of membrane • extracellular region • Cellbilen • integral component of plasma membrane • bilen • intracellular anatomical structure • extracellular space Prosesau biolegol • cell surface receptor signaling pathway • response to virus • receptor signaling pathway via JAK-STAT • regulation of type I interferon-mediated signaling pathway • type I interferon signaling pathway • response to interferon-alpha • response to interferon-beta • defense response to virus • cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3455	n/a
Ensembl	ENSG00000159110	n/a
UniProt	P48551	n/a
RefSeq (mRNA)	NM_207585 NM_000874 NM_001289125 NM_001289126 NM_001289128 NM_207584 NM_001385054 NM_001385055	n/a
RefSeq (protein)	NP_000865 NP_001276054 NP_001276055 NP_001276057 NP_997467 NP_997468	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IFNAR2 yw IFNAR2 a elwir hefyd yn Interferon alpha/beta receptor 2 ac Interferon alpha and beta receptor subunit 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 21, band 21q22.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IFNAR2.

• IFN-R
• IMD45
• IFNABR
• IFNARB
• IFN-alpha-REC

Llyfryddiaeth

• "Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expression. ". Eur J Immunol. 2017. PMID 27891600.
• "Detection of Interferon Alpha Receptor 2 in Interferon Resistant HCV Patients. ". Hepatogastroenterology. 2014. PMID 26176069.
• "Interferon (alpha, beta and omega) receptor 2 is a prognostic biomarker for lung cancer. ". Pathobiology. 2012. PMID 22236545.
• "Induction of type 1 interferon receptor by zinc in U937 cells. ". Cytokine. 2009. PMID 19362011.
• "Expression and regulation of IFNalpha/beta receptor in IFNbeta-treated patients with multiple sclerosis.". Neurology. 2008. PMID 18971450.