HTR2A

HTR2A
Dynodwyr
Cyfenwau	HTR2A, 5-HT2A, HTR2, 5-hydroxytryptamine receptor 2A
Dynodwyr allanol	OMIM: 182135 HomoloGene: 68073 GeneCards: HTR2A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding • G protein-coupled receptor activity • virus receptor activity • signal transducer activity • G-protein alpha-subunit binding • G protein-coupled serotonin receptor activity • serotonin binding • neurotransmitter receptor activity • GO:0001948, GO:0016582 protein binding • GO:0032403 protein-containing complex binding Cydrannau o'r gell • cytoplasm • integral component of membrane • cytosol • cell projection • bilen • cell body fiber • integral component of plasma membrane • dendritic shaft • axon • neuronal cell body • caveola • GO:0016023 cytoplasmic vesicle • Cellbilen • dendrite • glutamatergic synapse • integral component of postsynaptic membrane • integral component of presynaptic membrane Prosesau biolegol • detection of mechanical stimulus involved in sensory perception of pain • release of sequestered calcium ion into cytosol • regulation of dopamine secretion • phospholipase C-activating serotonin receptor signaling pathway • urinary bladder smooth muscle contraction • positive regulation of MAP kinase activity • behavioral response to cocaine • positive regulation of cytosolic calcium ion concentration • positive regulation of kinase activity • positive regulation of phosphatidylinositol biosynthetic process • GO:0010260 heneiddio • cellular calcium ion homeostasis • marwolaeth celloedd • Cof • activation of phospholipase C activity • detection of temperature stimulus involved in sensory perception of pain • protein localization to cytoskeleton • Cwsg • positive regulation of vasoconstriction • positive regulation of cell population proliferation • negative regulation of potassium ion transport • positive regulation of ERK1 and ERK2 cascade • artery smooth muscle contraction • positive regulation of peptidyl-tyrosine phosphorylation • viral entry into host cell • phosphatidylinositol 3-kinase signaling • sensory perception of pain • temperature homeostasis • GO:0022415 viral process • positive regulation of fat cell differentiation • positive regulation of glycolytic process • negative regulation of synaptic transmission, glutamatergic • GO:0072468 signal transduction • chemical synaptic transmission • serotonin receptor signaling pathway • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • GO:0035737 animal behaviour • regulation of synaptic vesicle exocytosis • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3356	n/a
Ensembl	ENSG00000102468	n/a
UniProt	P28223	n/a
RefSeq (mRNA)	NM_001165947 NM_000621 NM_001378924	n/a
RefSeq (protein)	NP_000612 NP_001159419 NP_001365853	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HTR2A yw HTR2A a elwir hefyd yn 5-hydroxytryptamine receptor 2A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 13, band 13q14.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HTR2A.

• HTR2
• 5-HT2A

Llyfryddiaeth

• "Relationship between Occupational Stress, 5-HT2A Receptor Polymorphisms and Mental Health in Petroleum Workers in the Xinjiang Arid Desert: A Cross-Sectional Study. ". Int J Environ Res Public Health. 2017. PMID 28394294.
• "Increased levels of 5HT2A receptor mRNA expression in peripheral blood mononuclear cells of patients with major depression: correlations with severity and duration of illness. ". Nord J Psychiatry. 2017. PMID 28125323.
• "Effect of 5-HT2A Receptor Polymorphisms, Work Stressors, and Social Support on Job Strain among Petroleum Workers in Xinjiang, China. ". Int J Environ Res Public Health. 2016. PMID 27999378.
• "Generation of neural cells using iPSCs from sleep bruxism patients with 5-HT2A polymorphism. ". J Prosthodont Res. 2017. PMID 27916472.
• "Serotonin 2A receptor (5-HT2A) gene promoter variant interacts with chronic perceived stress to modulate resting parasympathetic activity in humans.". Psychoneuroendocrinology. 2017. PMID 27912162.