HSPA2

HSPA2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3I33, 4FSV, 5FPM, 5FPN, 5FPD, 5FPE
Dynodwyr
Cyfenwau	HSPA2, HSP70-2, HSP70-3, heat shock protein family A (Hsp70) member 2
Dynodwyr allanol	OMIM: 140560 HomoloGene: 68564 GeneCards: HSPA2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • unfolded protein binding • GO:0001948, GO:0016582 protein binding • enzyme binding • ATP binding • disordered domain specific binding • glycolipid binding • ATPase activity • heat shock protein binding • protein folding chaperone activity • tau protein binding • chaperone binding • misfolded protein binding Cydrannau o'r gell • cytoplasm • cytosol • blood microparticle • bilen • spindle • extracellular exosome • Cytosgerbwd • cnewyllyn cell • synaptonemal complex • male germ cell nucleus • mitocondria • cell surface • CatSper complex • myelin sheath • meiotic spindle • Cellbilen Prosesau biolegol • cell differentiation • negative regulation of inclusion body assembly • response to heat • response to unfolded protein • protein refolding • spermatogenesis • response to cold • positive regulation of protein phosphorylation • male meiotic nuclear division • male meiosis I • spermatid development • positive regulation of ATP-dependent activity • synaptonemal complex disassembly • positive regulation of ATPase-coupled calcium transmembrane transporter activity • positive regulation of G2/M transition of mitotic cell cycle • vesicle-mediated transport • cellular response to heat • Unfolded Protein Response • chaperone cofactor-dependent protein refolding Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3306	n/a
Ensembl	ENSG00000126803	n/a
UniProt	P54652	n/a
RefSeq (mRNA)	NM_021979 NM_001387931	n/a
RefSeq (protein)	NP_068814	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HSPA2 yw HSPA2 a elwir hefyd yn Heat shock protein family A (Hsp70) member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HSPA2.

• HSP70-2
• HSP70-3

Llyfryddiaeth

• "Novel role for the testis-enriched HSPA2 protein in regulating epidermal keratinocyte differentiation. ". J Cell Physiol. 2018. PMID 28786487.
• "Heat shock protein 70-hom gene polymorphism and protein expression in multiple sclerosis. ". J Neuroimmunol. 2016. PMID 27609295.
• "Seminal plasma HSPA2 mRNA content is associated with semen quality. ". J Assist Reprod Genet. 2016. PMID 27209630.
• "Expression and clinical significance of HSPA2 in pancreatic ductal adenocarcinoma. ". Diagn Pathol. 2015. PMID 25890028.
• "The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition.". Asian J Androl. 2015. PMID 25865850.