HOXC6 Dynodwyr Cyfenwau HOXC6 , CP25, HHO.C8, HOX3, HOX3C, homeobox C6Dynodwyr allanol OMIM: 142972 HomoloGene: 19533 GeneCards: HOXC6 Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • sequence-specific DNA binding • DNA binding • GO:0001106 transcription corepressor activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • cytosol Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • anterior/posterior pattern specification • embryonic skeletal system development • negative regulation of nucleic acid-templated transcription • multicellular organism development • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau Species Bod dynol Llygoden Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Lleoliad (UCSC) n/a n/a PubMed search[1] n/a Wicidata
Protein sy'n cael ei godio yn y corff dynol gan y genyn HOXC6 yw HOXC6 a elwir hefyd yn Homeobox C6 (Saesneg). Segment o DNA yw'r genyn , sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q13.13.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HOXC6.
"The role of HOXC6 in prostate cancer development. ". Prostate . 2015. PMID 26310814 .
"Downregulation of HOXC6 in Serous Ovarian Cancer. ". Cancer Invest . 2015. PMID 26046583 .
"Upregulated Hoxc6 expression is associated with poor survival in gastric cancer patients. ". Neoplasma . 2013. PMID 23581417 .
"Loss of HOXC6 expression induces apoptosis in prostate cancer cells. ". Oncogene . 2005. PMID 15637592 .
"Cloning and expression of a new HOXC6 transcript encoding a repressing protein. ". Biochem J . 1996. PMID 8870653 .