HOXB5

HOXB5
Dynodwyr
Cyfenwau	HOXB5, HHO.C10, HOX2, HOX2A, HU-1, Hox2.1, homeobox B5
Dynodwyr allanol	OMIM: 142960 HomoloGene: 37585 GeneCards: HOXB5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Cydrannau o'r gell • fibrillar center • cnewyllyn cell • cytosol Prosesau biolegol • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • anatomical structure morphogenesis • transcription by RNA polymerase II • GO:0009373 regulation of transcription, DNA-templated • multicellular organism development • embryonic skeletal system development • endothelial cell differentiation • anterior/posterior pattern specification • embryonic skeletal system morphogenesis • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3215	n/a
Ensembl	ENSG00000120075	n/a
UniProt	P09067	n/a
RefSeq (mRNA)	NM_002147	n/a
RefSeq (protein)	NP_002138	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HOXB5 yw HOXB5 a elwir hefyd yn Homeobox B5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q21.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HOXB5.

• HOX2
• HU-1
• HOX2A
• Hox2.1
• HHO.C10

Llyfryddiaeth

• "HOXB5 induces invasion and migration through direct transcriptional up-regulation of β-catenin in human gastric carcinoma. ". Biochem J. 2015. PMID 26467157.
• "HOXB5 Promotes the Proliferation and Invasion of Breast Cancer Cells. ". Int J Biol Sci. 2015. PMID 25999793.
• "Roles of Hoxb5 in the development of vagal and trunk neural crest cells. ". Dev Growth Differ. 2015. PMID 25703667.
• "The transcription factor HoxB5 stimulates vascular remodelling in a cytokine-dependent manner. ". Cardiovasc Res. 2014. PMID 24189625.
• "HOXB5 expression in oral squamous cell carcinoma.". J Appl Oral Sci. 2011. PMID 21552713.