HOXB13

HOXB13
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CRA
Dynodwyr
Cyfenwau	HOXB13, PSGD, homeobox B13, HPC9
Dynodwyr allanol	OMIM: 604607 HomoloGene: 4640 GeneCards: HOXB13
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • methyl-CpG binding Cydrannau o'r gell • cnewyllyn cell • transcription regulator complex • nucleoplasm Prosesau biolegol • response to testosterone • morphogenesis of an epithelium • multicellular organism development • regulation of growth • GO:0009373 regulation of transcription, DNA-templated • response to wounding • prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis • angiogenesis • transcription, DNA-templated • epithelial cell maturation involved in prostate gland development • epidermis development • prostate gland development • GO:1901227 negative regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10481	n/a
Ensembl	ENSG00000159184	n/a
UniProt	Q92826	n/a
RefSeq (mRNA)	NM_006361	n/a
RefSeq (protein)	NP_006352	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HOXB13 yw HOXB13 a elwir hefyd yn Homeobox B13 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q21.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HOXB13.

• PSGD

Llyfryddiaeth

• "Hoxb13, a potential prognostic biomarker for prostate cancer. ". Front Biosci (Elite Ed). 2016. PMID 26709644.
• "HOXB13 as an immunohistochemical marker of prostatic origin in metastatic tumors. ". APMIS. 2016. PMID 26590121.
• "In silico analysis of the deleterious nsSNPs (missense) in the homeobox domain of human HOXB13 gene responsible for hereditary prostate cancer. ". Chem Biol Drug Des. 2017. PMID 28072499.
• "HOXB13 protein expression in metastatic lesions is a promising marker for prostate origin. ". Virchows Arch. 2016. PMID 26931741.
• "Prevalence of the HOXB13 G84E mutation in Danish men undergoing radical prostatectomy and its correlations with prostate cancer risk and aggressiveness.". BJU Int. 2016. PMID 26779768.