HOXA5

HOXA5
Dynodwyr
Cyfenwau	HOXA5, HOX1, HOX1.3, HOX1C, homeobox A5
Dynodwyr allanol	OMIM: 142952 HomoloGene: 40726 GeneCards: HOXA5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001948, GO:0016582 protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Cydrannau o'r gell • cnewyllyn cell Prosesau biolegol • embryonic skeletal system morphogenesis • pattern specification process • skeletal system development • respiratory system process • GO:0009373 regulation of transcription, DNA-templated • multicellular organism growth • lung development • trachea morphogenesis • bronchiole development • cell-cell signaling involved in mammary gland development • regulation of mammary gland epithelial cell proliferation • mammary gland alveolus development • lung goblet cell differentiation • transcription, DNA-templated • mammary gland epithelial cell differentiation • negative regulation of erythrocyte differentiation • respiratory gaseous exchange by respiratory system • trachea cartilage morphogenesis • embryonic skeletal system development • morphogenesis of an epithelium • multicellular organism development • thyroid gland development • lobar bronchus epithelium development • mesenchymal-epithelial cell signaling • positive regulation of apoptotic process • intestinal epithelial cell maturation • negative regulation of angiogenesis • cartilage morphogenesis • lung alveolus development • lung-associated mesenchyme development • epithelial tube branching involved in lung morphogenesis • cell migration • positive regulation of myeloid cell differentiation • anterior/posterior pattern specification • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3202	n/a
Ensembl	ENSG00000106004	n/a
UniProt	P20719	n/a
RefSeq (mRNA)	NM_019102	n/a
RefSeq (protein)	NP_061975	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HOXA5 yw HOXA5 a elwir hefyd yn Homeobox A5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p15.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HOXA5.

• HOX1
• HOX1C
• HOX1.3

Llyfryddiaeth

• "Knockdown of HOXA5 inhibits the tumorigenesis in esophageal squamous cell cancer. ". Biomed Pharmacother. 2017. PMID 27960137.
• "Effect of ATRA on the expression of HOXA5 gene in K562 cells and its relationship with cell cycle and apoptosis. ". Mol Med Rep. 2016. PMID 27052693.
• "Effect of silencing HOXA5 gene expression using RNA interference on cell cycle and apoptosis in Jurkat cells. ". Int J Mol Med. 2016. PMID 26846409.
• "Knockdown of homeobox A5 by small hairpin RNA inhibits proliferation and enhances cytarabine chemosensitivity of acute myeloid leukemia cells. ". Mol Med Rep. 2015. PMID 26397212.
• "HOXA5 inhibits metastasis via regulating cytoskeletal remodelling and associates with prolonged survival in non-small-cell lung carcinoma.". PLoS One. 2015. PMID 25875824.