HOPX

HOPX
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UHS, 2HI3
Dynodwyr
Cyfenwau	HOPX, CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO, HOP homeobox
Dynodwyr allanol	OMIM: 607275 HomoloGene: 15859 GeneCards: HOPX
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0001948, GO:0016582 protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cytoplasm • cnewyllyn cell Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • negative regulation of cell differentiation • multicellular organism development • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • trophectodermal cell differentiation • chaperone-mediated protein complex assembly • cell differentiation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	84525	n/a
Ensembl	ENSG00000171476	n/a
UniProt	Q9BPY8	n/a
RefSeq (mRNA)	NM_001145459 NM_001145460 NM_032495 NM_139211 NM_139212	n/a
RefSeq (protein)	NP_001138931 NP_001138932 NP_115884 NP_631957 NP_631958	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HOPX yw HOPX a elwir hefyd yn HOP homeobox (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HOPX.

• HOD
• HOP
• OB1
• LAGY
• TOTO
• CAMEO
• NECC1
• SMAP31

Llyfryddiaeth

• "Association between non-coding polymorphisms of HOPX gene and syncope in hypertrophic cardiomyopathy. ". Anadolu Kardiyol Derg. 2014. PMID 25036325.
• "Epigenetic silencing of HOPX promotes cancer progression in colorectal cancer. ". Neoplasia. 2012. PMID 22904674.
• "Epigenetic silencing of HOPX contributes to cancer aggressiveness in breast cancer. ". Cancer Lett. 2017. PMID 27756570.
• "Extracting a low-dimensional description of multiple gene expression datasets reveals a potential driver for tumor-associated stroma in ovarian cancer. ". Genome Med. 2016. PMID 27287041.
• "HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer.". J Pathol. 2015. PMID 25345926.