HNRNPD

HNRNPD
Strwythurau PDB Human UniProt search: D6RF44 PDBe D6RF44 RCSB Rhestr o ddynodwyr PDB 1HD0, 1HD1, 1IQT, 1WTB, 1X0F, 2Z5N
Dynodwyr
Cyfenwau	HNRNPD, AUF1, AUF1A, HNRPD, P37, hnRNPD0, heterogeneous nuclear ribonucleoprotein D
Dynodwyr allanol	OMIM: 601324 HomoloGene: 22410 GeneCards: HNRNPD
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • telomeric DNA binding • GO:0001948, GO:0016582 protein binding • minor groove of adenine-thymine-rich DNA binding • mRNA binding • histone deacetylase binding • transcription factor binding • chromatin binding • mRNA 3'-UTR AU-rich region binding • DNA binding • nucleic acid binding • RNA binding • sequence-specific DNA binding • sequence-specific double-stranded DNA binding Cydrannau o'r gell • cytoplasm • cytosol • extracellular exosome • nucleoplasm • cnewyllyn cell • synapse • ribonucleoprotein complex Prosesau biolegol • response to electrical stimulus • hepatocyte dedifferentiation • cellular response to amino acid stimulus • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • response to estradiol • mRNA stabilization • response to rapamycin • cellular response to putrescine • cerebellum development • negative regulation of gene expression • mRNA splicing, via spliceosome • positive regulation of translation • GO:0033168, GO:0036404, GO:1902360 RNA processing • liver development • transcription, DNA-templated • regulation of circadian rhythm • response to calcium ion • response to sodium phosphate • 3'-UTR-mediated mRNA destabilization • regulation of mRNA stability • cellular response to nitric oxide • proses rythmig • cellular response to estradiol stimulus • brain development • RNA catabolic process • circadian regulation of translation • GO:0009373 regulation of transcription, DNA-templated • GO:1901313 positive regulation of gene expression • mRNA transcription by RNA polymerase II • positive regulation of telomere capping • positive regulation of telomerase RNA reverse transcriptase activity • regulation of telomere maintenance • RNA metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3184	n/a
Ensembl	ENSG00000138668	n/a
UniProt	Q14103	n/a
RefSeq (mRNA)	NM_031370 NM_001003810 NM_002138 NM_031369	n/a
RefSeq (protein)	NP_001003810 NP_002129 NP_112737 NP_112738	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HNRNPD yw HNRNPD a elwir hefyd yn Heterogeneous nuclear ribonucleoprotein D0 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q21.22.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HNRNPD.

• P37
• AUF1
• AUF1A
• HNRPD
• hnRNPD0

Llyfryddiaeth

• "Arginine methylation enhances the RNA chaperone activity of the West Nile virus host factor AUF1 p45. ". RNA. 2016. PMID 27520967.
• "Crystal Structure of the N-Terminal RNA Recognition Motif of mRNA Decay Regulator AUF1. ". Biomed Res Int. 2016. PMID 27437398.
• "[The expression and significance of hnRNPD in esophageal squamous cell carcinoma cells]. ". Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2015. PMID 26648300.
• "Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer. ". J Transl Med. 2015. PMID 26318153.
• "Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells.". Free Radic Biol Med. 2015. PMID 25486179.