HMOX2

HMOX2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2Q32, 2QPP, 2RGZ, 4WMH
Dynodwyr
Cyfenwau	HMOX2, HO-2, heme oxygenase 2
Dynodwyr allanol	OMIM: 141251 HomoloGene: 1611 GeneCards: HMOX2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • oxidoreductase activity • GO:0001948, GO:0016582 protein binding • metal ion binding • heme oxygenase (decyclizing) activity • heme binding Cydrannau o'r gell • intracellular membrane-bounded organelle • endoplasmic reticulum membrane • bilen • Reticwlwm endoplasmig • Cellbilen • specific granule membrane Prosesau biolegol • response to hypoxia • cellular iron ion homeostasis • heme oxidation • GO:0001306 response to oxidative stress • heme catabolic process • neutrophil degranulation • iron ion homeostasis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3163	n/a
Ensembl	ENSG00000277424 ENSG00000103415	n/a
UniProt	P30519	n/a
RefSeq (mRNA)	NM_001127204 NM_001127205 NM_001127206 NM_001286267 NM_001286268 NM_001286269 NM_001286270 NM_001286271 NM_002134	n/a
RefSeq (protein)	NP_001120676 NP_001120677 NP_001120678 NP_001273196 NP_001273197 NP_001273198 NP_001273199 NP_001273200 NP_002125	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HMOX2 yw HMOX2 a elwir hefyd yn Heme oxygenase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HMOX2.

• HO-2

Llyfryddiaeth

• "Association between a heme oxygenase-2 genetic variant and risk of Parkinson's disease in Han Chinese. ". Neurosci Lett. 2017. PMID 28179208.
• "Heme Oxygenase 2 Binds Myristate to Regulate Retrovirus Assembly and TLR4 Signaling. ". Cell Host Microbe. 2017. PMID 28132836.
• "HMOX2 Functions as a Modifier Gene for High-Altitude Adaptation in Tibetans. ". Hum Mutat. 2016. PMID 26781569.
• "Spectroscopic studies reveal that the heme regulatory motifs of heme oxygenase-2 are dynamically disordered and exhibit redox-dependent interaction with heme. ". Biochemistry. 2015. PMID 25849895.
• "Role of cysteine residues in heme binding to human heme oxygenase-2 elucidated by two-dimensional NMR spectroscopy.". J Biol Chem. 2012. PMID 22923613.