HMGB1

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HMGB1
Protein HMGB1 PDB 1aab.png
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauHMGB1, HMG1, HMG3, SBP-1, HMG-1, high mobility group box 1
Dynodwyr allanolOMIM: 163905 HomoloGene: 110676 GeneCards: HMGB1
Patrwm RNA pattern
PBB GE HMGB1 214938 x at fs.png

PBB GE HMGB1 200680 x at fs.png

PBB GE HMGB1 200679 x at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001313892
NM_001313893
NM_002128

n/a

RefSeq (protein)

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HMGB1 yw HMGB1 a elwir hefyd yn High-mobility group box 1, isoform CRA_a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 13, band 13q12.3.[2]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HMGB1.

  • HMG1
  • HMG3
  • HMG-1
  • SBP-1

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "HMGB1 Expression Level in Circulating Platelets is not Significantly Associated with Outcomes in Symptomatic Coronary Artery Disease. ". Cell Physiol Biochem. 2017. PMID 29041001.
  • "Human Endothelial Progenitor Cell-Derived Exosomes Increase Proliferation and Angiogenesis in Cardiac Fibroblasts by Promoting the Mesenchymal-Endothelial Transition and Reducing High Mobility Group Box 1 Protein B1 Expression. ". DNA Cell Biol. 2017. PMID 28920705.
  • "High-mobility group box 1 released by autophagic cancer-associated fibroblasts maintains the stemness of luminal breast cancer cells. ". J Pathol. 2017. PMID 28802057.
  • "Roles of High Mobility Group Box 1 in Cardiovascular Calcification. ". Cell Physiol Biochem. 2017. PMID 28571029.
  • "Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy.". J Clin Invest. 2017. PMID 28504645.

Cyfeiriadau[golygu | golygu cod y dudalen]