HLA-DQB1

HLA-DQB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1JK8, 1S9V, 1UVQ, 2NNA, 4GG6
Dynodwyr
Cyfenwau	HLA-DQB1, CELIAC1, HLA-DQB, IDDM1, major histocompatibility complex, class II, DQ beta 1, HLA-DRB1
Dynodwyr allanol	OMIM: 604305 HomoloGene: 1603 GeneCards: HLA-DQB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptide antigen binding • MHC class II receptor activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • integral component of membrane • endocytic vesicle membrane • clathrin-coated endocytic vesicle membrane • endosome • Golgi apparatus • trans-Golgi network membrane • endoplasmic reticulum membrane • bilen • Golgi membrane • Cellbilen • transport vesicle membrane • MHC class II protein complex • lysosomal membrane • Reticwlwm endoplasmig • ER to Golgi transport vesicle membrane • lysosome • integral component of lumenal side of endoplasmic reticulum membrane • endosome membrane Prosesau biolegol • antigen processing and presentation • antigen processing and presentation of exogenous peptide antigen via MHC class II • interferon-gamma-mediated signaling pathway • immunoglobulin production involved in immunoglobulin-mediated immune response • immune system process • T cell costimulation • antigen processing and presentation of peptide or polysaccharide antigen via MHC class II • humoral immune response mediated by circulating immunoglobulin • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • T cell receptor signaling pathway • adaptive immune response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3119	n/a
Ensembl	ENSG00000233209 ENSG00000206237 ENSG00000231286 ENSG00000206302 ENSG00000179344 ENSG00000231939 ENSG00000225824	n/a
UniProt	P01920	n/a
RefSeq (mRNA)	NM_002123 NM_001243961 NM_001243962	n/a
RefSeq (protein)	NP_001230890 NP_001230891 NP_002114	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HLA-DQB1 yw HLA-DQB1 a elwir hefyd yn Major histocompatibility complex, class II, DQ beta 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HLA-DQB1.

• IDDM1
• CELIAC1
• HLA-DQB

Llyfryddiaeth

• "Is there a relationship between narcolepsy, multiple sclerosis and HLA-DQB1*06:02?". Arq Neuropsiquiatr. 2017. PMID 28658402.
• "Association of HLA-DQB1 polymorphisms with rheumatoid arthritis: a meta-analysis. ". Postgrad Med J. 2017. PMID 28455285.
• "Distribution of HLA-DQB1 in Czech Patients with Central Hypersomnias. ". Arch Immunol Ther Exp (Warsz). 2016. PMID 28083611.
• "HLA-DRB and HLA-DQB Allele and Haplotype Frequencies in Iranian Patients with Recurrent Aphthous Stomatitis. ". Iran J Allergy Asthma Immunol. 2016. PMID 27921409.
• "DQB1*060101 may contribute to susceptibility to immunoglobulin A nephropathy in southern Han Chinese.". Front Med. 2016. PMID 27896619.