HIVEP1

HIVEP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1BBO, 4ZNF
Dynodwyr
Cyfenwau	HIVEP1, CIRIP, CRYBP1, GAAP, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A, human immunodeficiency virus type I enhancer binding protein 1, HIVEP zinc finger 1
Dynodwyr allanol	OMIM: 194540 HomoloGene: 1596 GeneCards: HIVEP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • DNA binding • sequence-specific DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001948, GO:0016582 protein binding • metal ion binding • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cytoplasm • mitocondria • cnewyllyn cell • nucleoplasm • nuclear body Prosesau biolegol • multicellular organism development • GO:0009373 regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • GO:0072468 signal transduction • transcription, DNA-templated • BMP signaling pathway • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3096	n/a
Ensembl	ENSG00000095951	n/a
UniProt	P15822	n/a
RefSeq (mRNA)	NM_002114	n/a
RefSeq (protein)	NP_002105	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HIVEP1 yw HIVEP1 a elwir hefyd yn Human immunodeficiency virus type I enhancer binding protein 1 a Zinc finger protein 40 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p24.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HIVEP1.

• GAAP
• ZAS1
• CIRIP
• MBP-1
• ZNF40
• CRYBP1
• ZNF40A
• PRDII-BF1
• Schnurri-1

Llyfryddiaeth

• "A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1. ". Am J Hum Genet. 2010. PMID 20226436.
• "Novel zinc chelators with dual activity in the inhibition of the kappa B site-binding proteins HIV-EP1 and NF-kappa B. ". J Med Chem. 1995. PMID 7650680.
• "Putative metal finger structure of the human immunodeficiency virus type 1 enhancer binding protein HIV-EP1. ". J Biol Chem. 1989. PMID 2504707.
• "High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution. ". Biochemistry. 1990. PMID 2248949.
• "A large protein containing zinc finger domains binds to related sequence elements in the enhancers of the class I major histocompatibility complex and kappa immunoglobulin genes.". Mol Cell Biol. 1990. PMID 2108316.