HIST3H3

H3-4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2V1D, 2YBP, 2YBS, 3A6N, 3T6R, 4V2W
Dynodwyr
Cyfenwau	H3-4, H3.4, H3/g, H3FT, H3t, histone cluster 3, H3, histone cluster 3 H3, HIST3H3, H3.4 histone
Dynodwyr allanol	OMIM: 602820 HomoloGene: 133212 GeneCards: H3-4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein heterodimerization activity • DNA binding • GO:0031493 histone binding • GO:0001948, GO:0016582 protein binding • nucleosomal DNA binding Cydrannau o'r gell • nucleosome • extracellular exosome • cnewyllyn cell • Cromosom • nucleoplasm Prosesau biolegol • negative regulation of protein oligomerization • nucleosome assembly • protein heterotetramerization • double-strand break repair via nonhomologous end joining • telomere capping Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8290	n/a
Ensembl	ENSG00000168148 ENSG00000285435	n/a
UniProt	Q16695	n/a
RefSeq (mRNA)	NM_003493	n/a
RefSeq (protein)	NP_003484	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HIST3H3 yw HIST3H3 a elwir hefyd yn Histone cluster 3 H3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q42.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HIST3H3.

• H3t
• H3.4
• H3/g
• H3FT

Llyfryddiaeth

• "Dual roles of histone H3 lysine 9 acetylation in human embryonic stem cell pluripotency and neural differentiation. ". J Biol Chem. 2015. PMID 25519907.
• "Distinct chromatin signature of histone H3 variant H3.3 in human cells. ". Nucleus. 2014. PMID 25482197.
• "Epigenomic Landscape of Human Fetal Brain, Heart, and Liver. ". J Biol Chem. 2016. PMID 26719341.
• "Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain. ". Transl Psychiatry. 2015. PMID 26575220.
• "Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity.". Acta Neuropathol. 2016. PMID 26482474.